Is the level of HLA eplet mismatch a risk factor for graft loss among kidney transplant recipients who have already formed de novo donor specific antibody?

Is the level of HLA eplet mismatch a risk factor for graft loss among kidney transplant recipients who have already formed de novo donor specific antibody?

Is the level of HLA eplet mismatch a risk factor for graft loss among kidney transplant recipients who have already formed de novo donor specific antibody?

Eplet mismatches are related to de novo DSA (dnDSA) and antibody mediated rejection (ABMR) among the many common kidney transplant inhabitants. Nevertheless, it’s unclear whether or not the extent of eplet mismatch can be utilized for threat stratification amongst sufferers with dnDSA. We carried out a retrospective observational research of kidney transplant recipients with dnDSA (n = 44) transplanted between 10/2007 and 5/2014 to guage eplet mismatch as a threat issue for ABMR and allograft loss amongst dnDSA sufferers.

Excessive decision typing was inferred from by imputation primarily based on ethnicity and NMDP haplotypes, and the eplet mismatch was calculated utilizing the Epvix algorithm. Biopsies (N = 151) from 95.3%(42/44) of sufferers had been reviewed. The imply (SD) eplet mismatch was 69.8(22.8). The ABMR incidence was 71.4% (30/42) and 5 yr loss of life censored allograft survival was 67.4% throughout the imply (SD) follow-up of 5.3 (3.1) years. ABMR and death-censored allograft survival weren’t correlated with eplet mismatch amongst dnDSA sufferers.

Nevertheless, treatment adherence and dnDSA MFI < 3000 had been related to decreased ABMR incidence. Amongst sufferers with each of those favorable traits, solely 35.7% (15/42) developed ABMR. In conclusion, the extent of eplet mismatch doesn’t correlate with ABMR or allograft loss amongst excessive threat kidney transplant sufferers with dnDSA.

Excessive-throughput screening and validation of antibodies in opposition to synaptic proteins to discover opioid signaling dynamics

Antibodies symbolize highly effective instruments to look at sign transduction pathways. Right here, we current a technique integrating a number of state-of-the-art strategies to supply, validate, and make the most of antibodies. Specializing in understudied synaptic proteins, we generated 137 recombinant antibodies. We used yeast show antibody libraries from the B cells of immunized rabbits, adopted by FACS sorting beneath stringent circumstances to establish excessive affinity antibodies. The antibodies had been validated by high-throughput useful screening, and genome enhancing. Subsequent, we explored the temporal dynamics of signaling in single cells.
A subset of antibodies concentrating on opioid receptors had been used to look at the impact of therapy with opiates which have performed central roles within the worsening of the ‘opioid epidemic.’ We present that morphine and fentanyl exhibit differential temporal dynamics of receptor phosphorylation. In abstract, high-throughput approaches can result in the identification of antibody-based instruments required for an in-depth understanding of the temporal dynamics of opioid signaling.

SARS-CoV-2 B.1.1.7 sensitivity to mRNA vaccine-elicited, convalescent and monoclonal antibodies

Extreme Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) transmission is uncontrolled in lots of components of the world, compounded in some areas by increased transmission potential of the B1.1.7 variant now seen in 50 nations. It’s unclear whether or not responses to SARS-CoV-2 vaccines primarily based on the prototypic pressure will likely be impacted by mutations present in B.1.1.7. Right here we assessed immune responses following vaccination with mRNA-based vaccine BNT162b2. We measured neutralising antibody responses following a single immunization utilizing pseudoviruses expressing the wild-type Spike protein or the Eight amino acid mutations discovered within the B.1.1.7 spike protein.
The vaccine sera exhibited a broad vary of neutralising titres in opposition to the wild-type pseudoviruses that had been modestly decreased in opposition to B.1.1.7 variant. This discount was additionally evident in sera from some convalescent sufferers. Decreased B.1.1.7 neutralisation was additionally noticed with monoclonal antibodies concentrating on the N-terminal area (9 out of 10), the Receptor Binding Motif (RBM) (5 out of 31), however not in neutralising mAbs binding outdoors the RBM. Introduction of the E484Ok mutation in a B.1.1.7 background to replicate newly rising viruses within the UK led to a extra substantial lack of neutralising exercise by vaccine-elicited antibodies and mAbs (19 out of 31) over that conferred by the B.1.1.7 mutations alone. E484Ok emergence on a B.1.1.7 background represents a risk to the vaccine BNT162b.
Is the level of HLA eplet mismatch a risk factor for graft loss among kidney transplant recipients who have already formed de novo donor specific antibody?

Decreased neutralization of SARS-CoV-2 international variants by therapeutic anti-spike protein monoclonal antibodies

Monoclonal antibodies in opposition to the SARS-CoV-2 spike protein, notably, these developed by Regeneron Prescribed drugs and Eli Lilly and Firm have confirmed to supply safety in opposition to extreme COVID-19. The emergence of SARS-CoV-2 variants with closely mutated spike proteins raises the priority that the remedy might develop into much less efficient if any of the mutations disrupt epitopes engaged by the antibodies.
On this research, we examined monoclonal antibodies REGN10933 and REGN10987 which are utilized in mixture, for his or her capability to neutralize SARS-CoV-2 variants B.1.1.7, B.1.351, mink cluster 5 and COH.20G/677H. We report that REGN10987 maintains most of its neutralization exercise in opposition to viruses with B.1.1.7, B.1.351 and mink cluster 5 spike proteins however that REGN10933 has misplaced exercise in opposition to B.1.351 and mink cluster 5.
The failure of REGN10933 to neutralize B.1.351 is attributable to the Ok417N and E484Ok mutations within the receptor binding area; the failure to neutralize the mink cluster 5 spike protein is attributable to the Y453F mutation. The REGN10933 and REGN10987 mixture was 9.1-fold much less potent on B.1.351 and 16.2-fold much less potent on mink cluster 5, elevating considerations of decreased efficacy within the therapy of sufferers contaminated with variant viruses.

Mouse PLGF ELISA Kit

EMP0025 96Tests
EUR 625.2

PLGF (PGF) (PlGF-1/2) mouse monoclonal antibody, clone 178/G10, Purified

DM3525 100 µg Ask for price

Mouse PlGF-2 ELISA Kit

E16ME0045 96T
EUR 833.33

Rat Monoclonal anti-mouse PlGF

mAP-0010 100ug
EUR 250

PLGF (PGF) (PlGF-1/2) mouse monoclonal antibody, clone 178/G10, Biotin, Purified

DM3525B 50 µg Ask for price

Mouse PlGF Recombinant Protein

M30-019 5 µg
EUR 136.5
Description: Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF1, PlGF2 and PlGF3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF2 has been identified. Mouse PlGF shares 65% amino acid identity with human PlGF2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.

Mouse PlGF Recombinant Protein

M30-019S 2 µg
EUR 73.5
Description: Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF-1, PlGF-2 and PlGF-3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF-2 has been identified. Mouse PlGF shares 65% amino acid identity with human PlGF-2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.

Mouse PlGF Recombinant Protein

M30-020 20 µg
EUR 313.95
Description: Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF1, PlGF2 and PlGF3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF2 has been identified. Mouse PlGF shares 65% amino acid identity with human PlGF2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.

PLGF (Mouse, monoclonal, antagonistic)

mP1002r-m 100ug
EUR 467.5

Mouse PLGF-2 PicoKine ELISA Kit

EK0863 96 wells
EUR 510
Description: For Quantitative Detection of mouse PLGF-2 in cell culture supernates, serum and plasma (heparin, EDTA).

Anti-Rat PlGF Antibody

104-PA04AG 50 µg
EUR 157.5
Description: Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF1, PlGF2 and PlGF3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF2 has been identified. Mouse PlGF shares 65% amino acid identity with human PlGF2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.

Anti-Rat PlGF Antibody

104-PA04S 100 µg
EUR 126
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF-1), 152 (PlGF-2), and 203 (PlGF-3) amino acids (aa) respectively. Only PlGF-2 contains a highly basic heparin-binding 21 aa insert at the C-terminus. In rat only one PlGF that is the equivalent of human PlGF-2 has been identified. Rat PlGF shares 60%, 92%, 62% and 59% aa identity with the appropriate isoform of human, mouse, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during human pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt-1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2-mediated angiogenesis. However, PlGF (especially human PlGF-1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF-2, like VEGF164/165, shows heparin-dependent binding of neuropilin (Npn)-1 and Npn-2 and can inhibit nerve growth cone collapse. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis. Circulating PlGF often correlates with tumor stage and aggressiveness, and therapeutic PlGF antibodies are being investigated to inhibit tumor growth and angiogenesis.

PLGF (PGF) mouse monoclonal antibody, clone PLGF94, Purified

AM50307PU-S 100 µg Ask for price

PLGF (PGF) mouse monoclonal antibody, clone PLGF94, Purified

AM50307PU-T 20 µg Ask for price

Rabbit anti PlGF (human)

102-PA04AG 50ug
EUR 240

Rabbit anti PlGF (human)

102-PA04S 100ug
EUR 240

Rabbit Anti-Rat PlGF

104-PA04 100ug
EUR 240

Anti-Human PlGF Antibody

102-P248 100 µg
EUR 245.7
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF1), 152 (PlGF2), and 203 (PlGF3) amino acids (aa) respectively. Only PlGF2 contains a highly basic heparinbinding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF2 has been identified. Human PlGF1 shares 56%, 55%, 74% and 95% aa identity with the appropriate isoform of mouse, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2mediated angiogenesis. However, PlGF (especially PlGF1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF2, but not PLGF-1, shows heparindependent binding of neuropilin (Npn)-1 and Npn2. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis.

Anti-Human PlGF Antibody

101-MBi67 50 µg
EUR 189
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF1), 152 (PlGF2), and 203 (PlGF3) amino acids (aa) respectively. Only PlGF2 contains a highly basic heparinbinding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF2 has been identified. Human PlGF1 shares 56%, 55%, 74% and 95% aa identity with the appropriate isoform of mouse, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2mediated angiogenesis. However, PlGF (especially PlGF1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF2, but not PLGF-1, shows heparindependent binding of neuropilin (Npn)-1 and Npn2. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis.

Anti-Human PlGF Antibody

101-M03 100 µg
EUR 378
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF1), 152 (PlGF2), and 203 (PlGF3) amino acids (aa) respectively. Only PlGF2 contains a highly basic heparinbinding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF2 has been identified. Human PlGF1 shares 56%, 55%, 74% and 95% aa identity with the appropriate isoform of mouse, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2mediated angiogenesis. However, PlGF (especially PlGF1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF2, but not PLGF-1, shows heparindependent binding of neuropilin (Npn)-1 and Npn2. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis.

Anti-Human PlGF Antibody

101-M67 100 µg
EUR 189
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF1), 152 (PlGF2), and 203 (PlGF3) amino acids (aa) respectively. Only PlGF2 contains a highly basic heparinbinding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF2 has been identified. Human PlGF1 shares 56%, 55%, 74% and 95% aa identity with the appropriate isoform of mouse, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2mediated angiogenesis. However, PlGF (especially PlGF1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF2, but not PLGF-1, shows heparindependent binding of neuropilin (Npn)-1 and Npn2. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis.

Anti-Human PlGF Antibody

101-M69 100 µg
EUR 189
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF1), 152 (PlGF2), and 203 (PlGF3) amino acids (aa) respectively. Only PlGF2 contains a highly basic heparinbinding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF2 has been identified. Human PlGF1 shares 56%, 55%, 74% and 95% aa identity with the appropriate isoform of mouse, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2mediated angiogenesis. However, PlGF (especially PlGF1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF2, but not PLGF-1, shows heparindependent binding of neuropilin (Npn)-1 and Npn2. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis.

Anti-Human PlGF-2 Antibody

101-M65 100 µg
EUR 246.75
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF1), 152 (PlGF2), and 203 (PlGF3) amino acids (aa) respectively. Only PlGF2 contains a highly basic heparinbinding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF2 has been identified. Human PlGF1 shares 56%, 55%, 74% and 95% aa identity with the appropriate isoform of mouse, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2mediated angiogenesis. However, PlGF (especially PlGF1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF2, but not PLGF-1, shows heparindependent binding of neuropilin (Npn)-1 and Npn2. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis.

Anti-Human PlGF-2 Antibody

101-M65A 100 µg
EUR 246.75
Description: Placenta Growth Factor-2 (PlGF-2), a 22 kDa protein consisting of 152 amino acid residues is produced as a homodimer. PlGF is a polypeptide growth factor and a member of the platelet-derived growth factor family but more related to vascular endothelial growth factor (VEGF). PlGF acts only as a weak mitogen for those cell types possessing receptors for binding (e.g. vascular endothelial cells). At least one high-affinity receptor for PlGF (FLT-1 or VEGF-R1) has been demonstrated in different primary cell types (e.g. human umbilical vein endothelial cells and monocytes). In addition to its action as a weak mitogen it is also a chemoattractant for monocytes and endothelial cells. Three different proteins are generated by differential splicing of the human PlGF gene: PlGF-1 (131aa native chain), PlGF-2 (152aa) and PlGF-3 (203aa). All 3 mitogens are secretable proteins, but PlGF-2 can bind to heparin with high affinity. PlGF is apparently a homodimer, but preparations of PlGF show some heterogeneity on SDS gels depending of the varying degrees of glycosylation. All dimeric forms possess similar biological activities. Heterodimers between VEGF and PlGF are mitogenic for endothelial cells and have strong angiogenic activity in vivo (e.g. in the CAM assay or in the cornea pocket assay). Different cells and tissues (e.g. placenta) express PlGF-1 and PlGF-2 at different rates. A much related protein of PlGF is VEGF with about 53% homology and VEGF-B with similar biological activities.

Mouse PLGF / PGF Protein, His Tag

PGF-M52H0 50ug
EUR 3327.7
Description: Mouse PLGF, His Tag (PGF-M52H0) is expressed from human 293 cells (HEK293). It contains AA Val 19 - Pro 158 (Accession # P49764-1).

PLGF(PLGF93) Antibody

BNCH0093-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF93), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNCH0093-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF93), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNCH0094-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF94), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNCH0094-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF94), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNC700093-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF93), CF770 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNC700093-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF93), CF770 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNC700094-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF94), CF770 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNC700094-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF94), CF770 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNC800093-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF93), CF680 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNC800093-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF93), CF680 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNC800094-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF94), CF680 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNC800094-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF94), CF680 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNC810093-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF93), CF680R conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNC810093-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF93), CF680R conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNC810094-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF94), CF680R conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNC810094-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF94), CF680R conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNC550093-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF93), CF555 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNC550093-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF93), CF555 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNC550094-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF94), CF555 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNC550094-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF94), CF555 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNC610093-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF93), CF660R conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNC610093-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF93), CF660R conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNC610094-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF94), CF660R conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNC610094-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF94), CF660R conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNC430093-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF93), CF543 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNC430093-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF93), CF543 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNC430094-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF94), CF543 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNC430094-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF94), CF543 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNC050093-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF93), CF405M conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNC050093-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF93), CF405M conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNC050094-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF94), CF405M conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNC050094-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF94), CF405M conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNCA0093-250 250uL
EUR 459.6
Description: Primary antibody against PLGF(PLGF93), APC conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNCA0094-250 250uL
EUR 459.6
Description: Primary antibody against PLGF(PLGF94), APC conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNCAP0093-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF93), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNCAP0093-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF93), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNCAP0094-100 100uL
EUR 238.8
Description: Primary antibody against PLGF(PLGF94), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNCAP0094-500 500uL
EUR 652.8
Description: Primary antibody against PLGF(PLGF94), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNCP0093-250 250uL
EUR 459.6
Description: Primary antibody against PLGF(PLGF93), PerCP conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNCP0094-250 250uL
EUR 459.6
Description: Primary antibody against PLGF(PLGF94), PerCP conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody

BNCR0093-250 250uL
EUR 459.6
Description: Primary antibody against PLGF(PLGF93), RPE conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody

BNCR0094-250 250uL
EUR 459.6
Description: Primary antibody against PLGF(PLGF94), RPE conjugate, Concentration: 0.1mg/mL

OKRC01283-96W - PLGF-2 ELISA Kit (Mouse)

OKRC01283-96W 96Wells
EUR 525

Anti-Human PlGF (native) Antibody

102-PABi04 50 µg
EUR 157.5
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF1), 152 (PlGF2), and 203 (PlGF3) amino acids (aa) respectively. Only PlGF2 contains a highly basic heparinbinding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF2 has been identified. Human PlGF1 shares 56%, 55%, 74% and 95% aa identity with the appropriate isoform of mouse, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2mediated angiogenesis. However, PlGF (especially PlGF1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF2, but not PLGF-1, shows heparindependent binding of neuropilin (Npn)-1 and Npn2. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis.

PLGF

E8EM1701-88 100ul
EUR 275
Description: Available in various conjugation types.

PLGF

E8EM1701-90 100ul
EUR 275
Description: Available in various conjugation types.

PLGF

E8ER1706-88 100ul
EUR 275
Description: Available in various conjugation types.

PLGF

E8ET1704-99 100ul
EUR 275
Description: Available in various conjugation types.

PLGF

PA1066-M 100μg
EUR 290
Description: Polyclonal Antibodies Conjugated to Magnetic Beads

PLGF

PA1066-S 100μg
EUR 290
Description: Polyclonal Antibodies Conjugated to Sepharose Beads

PLGF

PA1066 100μg
EUR 260

Anti-Human PlGF (Peptide) Antibody

102-PA01S 100 µg
EUR 115.5
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF1), 152 (PlGF2), and 203 (PlGF3) amino acids (aa) respectively. Only PlGF2 contains a highly basic heparinbinding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF2 has been identified. Human PlGF1 shares 56%, 55%, 74% and 95% aa identity with the appropriate isoform of mouse, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2mediated angiogenesis. However, PlGF (especially PlGF1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF2, but not PLGF-1, shows heparindependent binding of neuropilin (Npn)-1 and Npn2. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis.

Rabbit Anti-Human PlGF (native)

102-PA04 100ug
EUR 240

Polyclonal Anti-PGF (PLGF) Antibody

GWB-BBP088 0.1 mg Ask for price

PLGF Antibody

E8RT1505 100ul
EUR 225
Description: Available in various conjugation types.

PLGF Antibody

49602 100ul
EUR 499

PLGF Antibody

49602-100ul 100ul
EUR 399.6

PLGF Antibody

49602-50ul 50ul
EUR 286.8

PlGF antibody

70R-12427 100 ug
EUR 371
Description: Rabbit polyclonal PlGF antibody

PlGF Antibody

5743-100 each
EUR 405.6

PlGF Antibody

5743-30T each
EUR 175.2

PLGF Antibody

GWB-628116 0.1 mg Ask for price

PLGF Antibody

R30247 100 ug
EUR 356.15
Description: Placental growth factor(PGF, also known as PLGF) codes for an angiogenic factor expressed in placental tissue that is similar to vascular permeability factor/vascular endothelial growth factor(VPF/VEGF). It is a glycosylated dimeric secreted protein able to stimulate endothelial cell growth in vitro. PGF is located on chromosome 14 and has been conserved in evolution. It belongs to the family of vascular endothelial growth factors(VEGFs) and binds to the flt-1 VEGF receptor. PLGF-2, which is a PLGF isoform, binds neuropilin-1 and 2 in a heparin-dependent manner. PGF regulates inter- and intra molecular cross talk between the VEGF RTKs Flt1 and Flk1 and stimulates the phosphorylation of specific Flt1 tyrosine residues and the expression of distinct downstream target genes. Moreover, it plays an important role in pathological angiogenic events and with exerting its biological activities through binding to VEGFR1.

PLGF Antibody

R34945-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Placental growth factor; PGF

Rabbit Anti-Human PlGF (Peptide)

102-PA01 100ug
EUR 240

Sheep Polyclonal anti-human PlGF

hAP-5406 50ug
EUR 400

PlGF-1 Antibody

5739-100 each
EUR 405.6

PlGF-1 Antibody

5739-30T each
EUR 175.2

Mouse Placenta Growth Factor (PLGF) Protein

20-abx068553
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Placenta Growth Factor (PLGF) Protein

abx068553-20g 20 µg
EUR 562.5

Mouse Placenta Growth Factor (PLGF) Protein

abx068553-5g 5 µg
EUR 287.5

Placenta Growth Factor (PLGF) Polyclonal Antibody (Mouse)

4-PAA114Mu01
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Placenta Growth Factor (PLGF)

Mouse PLGF(Placenta Growth Factor) ELISA Kit

ELK1242-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PLGF. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PLGF. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse PLGF, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse PLGF in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse PLGF(Placenta Growth Factor) ELISA Kit

ELK1242-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PLGF. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PLGF. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse PLGF, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse PLGF in the samples is then determined by comparing the OD of the samples to the standard curve.

human anti-human PLGF mAb (AB1)

E4A09J01-AB1 50ug
EUR 255
Description: Available in various conjugation types.

human anti-human PLGF mAb (AB2)

E4A09J01-AB2 50ug
EUR 255
Description: Available in various conjugation types.

human anti-human PLGF mAb(AB7)

E4A09J01-AB7 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human PLGF mAb(AB8)

E4A09J01-AB8 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Mouse Placenta Growth Factor (PLGF) ELISA Kit

DLR-PLGF-Mu 96T
EUR 241
Description: serum, plasma, tissue homogenates or other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit

DLR-PLGF-Mu-48T 48T
EUR 380.4
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Placenta Growth Factor (PLGF) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit

DLR-PLGF-Mu-96T 96T
EUR 477.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Placenta Growth Factor (PLGF) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse placenta growth factor,PLGF Elisa kit

EK731467 96 Wells
EUR 0.79

Mouse Placenta growth factor, PlGF ELISA Kit

ELA-E0114m 96 Tests
EUR 1038

Mouse Placenta Growth Factor (PLGF) ELISA Kit

EKN47757-48T 48T
EUR 269.71

Mouse Placenta Growth Factor (PLGF) ELISA Kit

EKN47757-5x96T 5x96T
EUR 1830.18

Mouse Placenta Growth Factor (PLGF) ELISA Kit

EKN47757-96T 96T
EUR 385.3

Mouse Placenta Growth Factor (PLGF) ELISA Kit

EKL54888-5x96T 5x96T
EUR 1883.38

Mouse Placenta Growth Factor (PLGF) ELISA Kit

EKL54888-96T 96T
EUR 396.5

Mouse Placenta Growth Factor (PLGF) ELISA Kit

EKU06646-48T 48T
EUR 395.36

Mouse Placenta Growth Factor (PLGF) ELISA Kit

EKU06646-5x96T 5x96T
EUR 2682.8

Mouse Placenta Growth Factor (PLGF) ELISA Kit

EKU06646-96T 96T
EUR 564.8

Mouse placenta growth factor(PLGF)ELISA Kit  

GA-E0088MS-48T 48T
EUR 403.2

Mouse placenta growth factor(PLGF)ELISA Kit  

GA-E0088MS-96T 96T
EUR 640.8

Mouse Placenta Growth Factor (PLGF) ELISA Kit

DL-PLGF-Mu 96T
EUR 230
Description: serum, plasma, tissue homogenates or other biological fluids.

Mouse placenta growth factor, PLGF ELISA kit

CSB-E07401m-24T 1 plate of 24 wells
EUR 198
Description: Quantitativecompetitive ELISA kit for measuring Mouse placenta growth factor, PLGF in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse placenta growth factor, PLGF ELISA kit

1-CSB-E07401m
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  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Mouse placenta growth factor, PLGF in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Placenta growth factor (PLGF) ELISA Kit

AE27811MO-48Tests 48 Tests
EUR 305
Description: Mouse (Mus musculus)

Mouse Placenta growth factor (PLGF) ELISA Kit

AE27811MO-96Tests 96 Tests
EUR 570
Description: Mouse (Mus musculus)

Mouse placenta growth factor,PLGF ELISA kit

CN-02373M1 96T
EUR 565.2

Mouse placenta growth factor,PLGF ELISA kit

CN-02373M2 48T
EUR 386.4

Mouse Placenta Growth Factor (PLGF) ELISA Kit

RD-PLGF-Mu-48T 48T
EUR 235.7
Description: serum, plasma, tissue homogenates and other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit

RD-PLGF-Mu-48Tests 48 Tests
EUR 354

Mouse Placenta Growth Factor (PLGF) ELISA Kit

RD-PLGF-Mu-96T 96T
EUR 336.7
Description: serum, plasma, tissue homogenates and other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit

RD-PLGF-Mu-96Tests 96 Tests
EUR 480

Mouse Placenta growth factor (PLGF) ELISA Kit

RK06233 96T
EUR 280

Mouse placenta growth factor(PLGF)ELISA Kit

QY-E21188 96T
EUR 433.2

Mouse Placenta Growth Factor (PLGF)ELISA Kit

NSL1327m 96 Test
EUR 528

Mouse Placenta Growth Factor (PLGF) ELISA Kit

RDR-PLGF-Mu-48T 48T
EUR 247.49
Description: serum, plasma, tissue homogenates and other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit

RDR-PLGF-Mu-48Tests 48 Tests
EUR 368.4

Mouse Placenta Growth Factor (PLGF) ELISA Kit

RDR-PLGF-Mu-96T 96T
EUR 353.54
Description: serum, plasma, tissue homogenates and other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit

RDR-PLGF-Mu-96Tests 96 Tests
EUR 501.6

Mouse Placenta Growth Factor (PLGF) ELISA Kit

SEA114Mu-10x96wellstestplate 10x96-wells test plate
EUR 4091.29
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Placenta Growth Factor (PLGF) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit

SEA114Mu-1x48wellstestplate 1x48-wells test plate
EUR 442.1
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Placenta Growth Factor (PLGF) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit

SEA114Mu-1x96wellstestplate 1x96-wells test plate
EUR 580.15
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Placenta Growth Factor (PLGF) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit

SEA114Mu-5x96wellstestplate 5x96-wells test plate
EUR 2250.68
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Placenta Growth Factor (PLGF) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit

4-SEA114Mu
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  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Placenta Growth Factor (PLGF) in samples from Serum, plasma, tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse placenta growth factor,PLGF ELISA kit  

YLA0480MO-48T 48T Ask for price

Mouse placenta growth factor,PLGF ELISA kit  

YLA0480MO-96T 96T Ask for price

Anti-Human PlGF-1 Rabbit Polyclonal Antibody

TA328423 100 µg Ask for price

Placenta Growth Factor (PLGF) Polyclonal Antibody (Mouse), PE

4-PAA114Mu01-PE
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Placenta Growth Factor (PLGF). This antibody is labeled with PE.

h. PLGF

EK0490 1×96T
EUR 550
Description: ELISA

Placenta Growth Factor (PLGF) Polyclonal Antibody (Mouse), APC

4-PAA114Mu01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Placenta Growth Factor (PLGF). This antibody is labeled with APC.

Placenta Growth Factor (PLGF) Polyclonal Antibody (Mouse), Cy3

4-PAA114Mu01-Cy3
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Placenta Growth Factor (PLGF). This antibody is labeled with Cy3.

Placenta Growth Factor (PLGF) Polyclonal Antibody (Mouse), HRP

4-PAA114Mu01-HRP
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Placenta Growth Factor (PLGF). This antibody is labeled with HRP.

PLGF, His

cyt-1031 2µg
EUR 60
Description: Recombinant Human Placental Growth Factor, His Tag

PLGF, HEK

cyt-1193 2µg
EUR 60
Description: Recombinant Human Placental Growth Factor

Recombinant Mouse PLGF/PGF Protein, Fc & His Tag

E40KMP1764 20ug
EUR 495

Placenta Growth Factor (PLGF) Polyclonal Antibody (Mouse), FITC

4-PAA114Mu01-FITC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Placenta Growth Factor (PLGF). This antibody is labeled with FITC.

ELISA kit for Mouse PLGF (Placenta Growth Factor)

ELK1242 1 plate of 96 wells
EUR 446.4
Description: A sandwich ELISA kit for detection of Placenta Growth Factor from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

PLGF Antibody (Biotin)

GWB-B31F12 0.05 mg Ask for price

PLGF (PGF) mouse monoclonal antibody, clone 331/H12, Purified

DM3526 100 µg Ask for price

PLGF protein

30R-2693 10 ug
EUR 265
Description: Purified recombinant Mouse PLGF protein

PLGF Peptide

42-184P 0.1 mg
EUR 405.6
Description: (IN) PLGF Peptide

PLGF (PGF) mouse monoclonal antibody, clone 342/3B10, Purified

DM3524 100 µg Ask for price

PLGF(PLGF93), 1mg/mL

BNUM0093-50 50uL
EUR 396
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

PLGF(PLGF94), 1mg/mL

BNUM0094-50 50uL
EUR 396
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

PLGF(PLGF93), 0.2mg/mL

BNUB0093-100 100uL
EUR 225
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

PLGF(PLGF93), 0.2mg/mL

BNUB0093-500 500uL
EUR 485
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

PLGF(PLGF94), 0.2mg/mL

BNUB0094-100 100uL
EUR 225
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

PLGF(PLGF94), 0.2mg/mL

BNUB0094-500 500uL
EUR 485
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Polyclonal PlGF-1 Antibody

AMR09383G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PlGF-1 . This antibody is tested and proven to work in the following applications:

Polyclonal PlGF Antibody

AMR09382G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PlGF . This antibody is tested and proven to work in the following applications:

PLGF Conjugated Antibody

C49602 100ul
EUR 476.4

PLGF Polyclonal Antibody

A72122 50 μl
EUR 408

PLGF Polyclonal Antibody

A72123 50 μl
EUR 408

Placenta Growth Factor (PLGF) Polyclonal Antibody (Mouse), Biotinylated

4-PAA114Mu01-Biotin
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Placenta Growth Factor (PLGF). This antibody is labeled with Biotin.

ELISA kit for Mouse Placenta growth factor (PLGF)

KTE70764-48T 48T
EUR 457.2
Description: Quantitative sandwich ELISA for measuring Mouse Placenta growth factor (PLGF) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Placenta growth factor (PLGF)

KTE70764-5platesof96wells 5 plates of 96 wells
EUR 3194.4
Description: Quantitative sandwich ELISA for measuring Mouse Placenta growth factor (PLGF) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Placenta growth factor (PLGF)

KTE70764-96T 96T
EUR 802.8
Description: Quantitative sandwich ELISA for measuring Mouse Placenta growth factor (PLGF) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Placenta Growth Factor (PLGF) Polyclonal Antibody (Mouse), APC-Cy7

4-PAA114Mu01-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Placenta Growth Factor (PLGF). This antibody is labeled with APC-Cy7.

Biotinylated Anti-Human PlGF-1 Rabbit Polyclonal Antibody

TA328422 50 µg Ask for price

PLGF Rabbit pAb

E2381909 100ul
EUR 225
Description: Available in various conjugation types.

PLGF Rabbit mAb

E2R22802 100ul
EUR 255
Description: Available in various conjugation types.

PLGF Rabbit pAb

E2382802 100ul
EUR 225
Description: Available in various conjugation types.

PLGF Rabbit pAb

A16257-100ul 100 ul
EUR 369.6

PLGF Rabbit pAb

A16257-200ul 200 ul
EUR 550.8

PLGF Rabbit pAb

A16257-20ul 20 ul
EUR 219.6

PLGF Rabbit pAb

A16257-50ul 50 ul
EUR 267.6

PLGF Rabbit pAb

A1727-100ul 100 ul
EUR 369.6

PLGF Rabbit pAb

A1727-200ul 200 ul
EUR 550.8

PLGF Rabbit pAb

A1727-20ul 20 ul
EUR 219.6

PLGF Rabbit pAb

A1727-50ul 50 ul
EUR 267.6

PLGF Rabbit mAb

59530 100ul
EUR 339

PLGF Rabbit mAb

A2400 200μL
EUR 323.7
Description: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Activator protein 2 (AP-2/TFAP2A) (P05549).

PLGF Rabbit Polyclonal Antibody

54165 100ul
EUR 439

Rabbit Polyclonal PLGF Antibody

TA590677 100 µg Ask for price

PLGF Rabbit Monoclonal Antibody

E10G20933 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

PLGF Rabbit Polyclonal Antibody

E10G22947 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Recombinant Human PlGF

Z102615 25 µg
EUR 105
Description: Human PlGF, or Placental Growth Factor, is part of the PDGF/VEGF family and contains the 8 cysteine residues conserved in the family. It can be alternately spliced into three different mature forms. PGF is typically found as a disulfide linked dimer which is highly glycosylated. It is a key molecule involved in vasculogenesis and angiogenesis, especially during embryogenesis. It also induces the activation of monocytes, as well as their migration and production of inflammatory cytokines. It is primarily expressed by the placental trophoblast during pregnancy, but is also expressed in villious trophoblasts, decidual cells, erythroblasts, keratinocytes, and somewhat in endothelial cells. PGF signals by binding VEGF R1, and competes with VEGF for binding. Recombinant PlGF is a 15.0 kDa protein.

Recombinant Human PlGF

Z102617 4 x 25 µg (Z102615 x 4)
EUR 265
Description: Human PlGF, or Placental Growth Factor, is part of the PDGF/VEGF family and contains the 8 cysteine residues conserved in the family. It can be alternately spliced into three different mature forms. PGF is typically found as a disulfide linked dimer which is highly glycosylated. It is a key molecule involved in vasculogenesis and angiogenesis, especially during embryogenesis. It also induces the activation of monocytes, as well as their migration and production of inflammatory cytokines. It is primarily expressed by the placental trophoblast during pregnancy, but is also expressed in villious trophoblasts, decidual cells, erythroblasts, keratinocytes, and somewhat in endothelial cells. PGF signals by binding VEGF R1, and competes with VEGF for binding. Recombinant PlGF is a 15.0 kDa protein.

Recombinant Human PlGF

Z102619 1.0 mg
EUR 3900
Description: Human PlGF, or Placental Growth Factor, is part of the PDGF/VEGF family and contains the 8 cysteine residues conserved in the family. It can be alternately spliced into three different mature forms. PGF is typically found as a disulfide linked dimer which is highly glycosylated. It is a key molecule involved in vasculogenesis and angiogenesis, especially during embryogenesis. It also induces the activation of monocytes, as well as their migration and production of inflammatory cytokines. It is primarily expressed by the placental trophoblast during pregnancy, but is also expressed in villious trophoblasts, decidual cells, erythroblasts, keratinocytes, and somewhat in endothelial cells. PGF signals by binding VEGF R1, and competes with VEGF for binding. Recombinant PlGF is a 15.0 kDa protein.

PLGF-1, human recombinant

4739-100 each
EUR 836.4

PLGF-1, human recombinant

4739-1000 each
EUR 3909.6

PLGF-1, human recombinant

4739-25 each
EUR 307.2

PLGF-2, human recombinant

4741-10 each
EUR 307.2

PLGF-2, human recombinant

4741-1000 each
EUR 4105.2
The outcomes recommend that there’s a must develop further monoclonal antibodies that aren’t affected by the present spike protein mutations.
Antibodies where obtained from Orla Proteins Ltd. London.

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