Integrin Research The Martin Humphries Lab

Antibodies symbolize highly effective instruments to look at sign transduction pathways. Right here, we current a technique integrating a number of state-of-the-art strategies to supply, validate, and make the most of antibodies. Specializing in understudied synaptic proteins, we generated 137 recombinant antibodies. We used yeast show antibody libraries from the B cells of immunized rabbits, adopted by FACS sorting beneath stringent circumstances to establish excessive affinity antibodies. The antibodies had been validated by high-throughput useful screening, and genome enhancing. Subsequent, we explored the temporal dynamics of signaling in single cells.

A subset of antibodies concentrating on opioid receptors had been used to look at the impact of therapy with opiates which have performed central roles within the worsening of the ‘opioid epidemic.’ We present that morphine and fentanyl exhibit differential temporal dynamics of receptor phosphorylation. In abstract, high-throughput approaches can result in the identification of antibody-based instruments required for an in-depth understanding of the temporal dynamics of opioid signaling.

Extreme Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) transmission is uncontrolled in lots of components of the world, compounded in some areas by increased transmission potential of the B1.1.7 variant now seen in 50 nations. It’s unclear whether or not responses to SARS-CoV-2 vaccines primarily based on the prototypic pressure will likely be impacted by mutations present in B.1.1.7. Right here we assessed immune responses following vaccination with mRNA-based vaccine BNT162b2. We measured neutralising antibody responses following a single immunization utilizing pseudoviruses expressing the wild-type Spike protein or the Eight amino acid mutations discovered within the B.1.1.7 spike protein.

The vaccine sera exhibited a broad vary of neutralising titres in opposition to the wild-type pseudoviruses that had been modestly decreased in opposition to B.1.1.7 variant. This discount was additionally evident in sera from some convalescent sufferers. Decreased B.1.1.7 neutralisation was additionally noticed with monoclonal antibodies concentrating on the N-terminal area (9 out of 10), the Receptor Binding Motif (RBM) (5 out of 31), however not in neutralising mAbs binding outdoors the RBM. Introduction of the E484Ok mutation in a B.1.1.7 background to replicate newly rising viruses within the UK led to a extra substantial lack of neutralising exercise by vaccine-elicited antibodies and mAbs (19 out of 31) over that conferred by the B.1.1.7 mutations alone. E484Ok emergence on a B.1.1.7 background represents a risk to the vaccine BNT162b.

Monoclonal antibodies in opposition to the SARS-CoV-2 spike protein, notably, these developed by Regeneron Prescribed drugs and Eli Lilly and Firm have confirmed to supply safety in opposition to extreme COVID-19. The emergence of SARS-CoV-2 variants with closely mutated spike proteins raises the priority that the remedy might develop into much less efficient if any of the mutations disrupt epitopes engaged by the antibodies.

On this research, we examined monoclonal antibodies REGN10933 and REGN10987 which are utilized in mixture, for his or her capability to neutralize SARS-CoV-2 variants B.1.1.7, B.1.351, mink cluster 5 and COH.20G/677H. We report that REGN10987 maintains most of its neutralization exercise in opposition to viruses with B.1.1.7, B.1.351 and mink cluster 5 spike proteins however that REGN10933 has misplaced exercise in opposition to B.1.351 and mink cluster 5.

The failure of REGN10933 to neutralize B.1.351 is attributable to the Ok417N and E484Ok mutations within the receptor binding area; the failure to neutralize the mink cluster 5 spike protein is attributable to the Y453F mutation. The REGN10933 and REGN10987 mixture was 9.1-fold much less potent on B.1.351 and 16.2-fold much less potent on mink cluster 5, elevating considerations of decreased efficacy within the therapy of sufferers contaminated with variant viruses.

Mouse Anti-Human PlGF-2
MBS690323-01mg	MyBiosource	0.1mg	EUR 450

Mouse Anti-Human PlGF-2
MBS690323-5x01mg	MyBiosource	5x0.1mg	EUR 1725

Mouse Anti-Human PlGF-2
MBS692571-01mg	MyBiosource	0.1mg	EUR 450

Mouse Anti-Human PlGF-2
MBS692571-5x01mg	MyBiosource	5x0.1mg	EUR 1725

Mouse Monoclonal anti-human PlGF
hAP-0010	Angio Proteomie	100ug	EUR 250

Mouse PlGF
MBS691520-0002mg	MyBiosource	0.002mg	EUR 265

Mouse PlGF
MBS691520-5x0002mg	MyBiosource	5x0.002mg	EUR 890

Mouse PlGF
MBS692108-0005mg	MyBiosource	0.005mg	EUR 350

Mouse PlGF
MBS692108-5x0005mg	MyBiosource	5x0.005mg	EUR 1275

Mouse PlGF
MBS692180-002mg	MyBiosource	0.02mg	EUR 625

Mouse PlGF
MBS692180-5x002mg	MyBiosource	5x0.02mg	EUR 2510

Mouse Monoclonal anti-Human PlGF Antibody
xAP-0457	Angio Proteomie	100ug	EUR 280

Anti-Mouse PlGF Antibody
103-M03	ReliaTech	100 µg	EUR 399
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF-1), 152 (PlGF-2), and 203 (PlGF-3) amino acids (aa) respectively. Only PlGF-2 contains a highly basic heparin-binding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF-2 has been identified. Mouse PlGF shares 60%, 92%, 62% and 59% aa identity with the appropriate isoform of human, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during human pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt-1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2-mediated angiogenesis. However, PlGF (especially human PlGF-1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF-2, like VEGF164/165, shows heparin-dependent binding of neuropilin (Npn)-1 and Npn-2 and can inhibit nerve growth cone collapse. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis. Circulating PlGF often correlates with tumor stage and aggressiveness, and therapeutic P lGF antibodies are being investigated to inhibit tumor growth and angiogenesis.

Anti-Mouse PlGF Antibody
103-PA04AG	ReliaTech	50 µg	EUR 157.5
Description: Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF1, PlGF2 and PlGF3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF2 has been identified. Mouse PlGF shares 65% amino acid identity with human PlGF2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.

Anti-Mouse PlGF Antibody
103-PA04S	ReliaTech	100 µg	EUR 126
Description: Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF1, PlGF2 and PlGF3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF2 has been identified. Mouse PlGF shares 65% amino acid identity with human PlGF2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.

Anti-Mouse PlGF Antibody
MBS4158465-01mg	MyBiosource	0.1mg	EUR 1255

Anti-Mouse PlGF Antibody
MBS4158465-5x01mg	MyBiosource	5x0.1mg	EUR 5390

Rabbit Anti-Mouse PlGF
103-PA04	Angio Proteomie	100ug	EUR 240

Anti-Human PGF/PlGF/PLGF Nanobody
MBS1568114-01mg	MyBiosource	0.1mg	EUR 405

Anti-Human PGF/PlGF/PLGF Nanobody
MBS1568114-5x01mg	MyBiosource	5x0.1mg	EUR 1520

Mouse PLGF ELISA Kit
EMP0025	Abclonal	96Tests	EUR 625.2

Mouse PlGF Rabbit pAb
A24547	Abclonal	20μL	EUR 262.15

PLGF (PGF) (PlGF-1/2) mouse monoclonal antibody, clone 178/G10, Purified
DM3525	Origene Technologies GmbH	100 µg	Ask for price

Mouse PlGF-2 ELISA Kit
E16ME0045	EnoGene	96T	EUR 833.33

Mouse PlGF-2 ELISA Kit
MBS8291429-5x96Tests	MyBiosource	5x96Tests	EUR 2755

Mouse PlGF-2 ELISA Kit
MBS8291429-96Tests	MyBiosource	96Tests	EUR 620

Mouse PlGF Recombinant Protein
M30-019	ReliaTech	5 µg	EUR 136.5
Description: Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF1, PlGF2 and PlGF3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF2 has been identified. Mouse PlGF shares 65% amino acid identity with human PlGF2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.

Mouse PlGF Recombinant Protein
M30-019S	ReliaTech	2 µg	EUR 73.5
Description: Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF-1, PlGF-2 and PlGF-3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF-2 has been identified. Mouse PlGF shares 65% amino acid identity with human PlGF-2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.

Mouse PlGF Recombinant Protein
M30-020	ReliaTech	20 µg	EUR 313.95
Description: Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF1, PlGF2 and PlGF3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF2 has been identified. Mouse PlGF shares 65% amino acid identity with human PlGF2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.

PLGF (Mouse, monoclonal, antagonistic)
mP1002r-m	Angio Proteomie	100ug	EUR 467.5

PLGF (PGF) (PlGF-1/2) mouse monoclonal antibody, clone 178/G10, Biotin, Purified
DM3525B	Origene Technologies GmbH	50 µg	Ask for price

Rat Monoclonal anti-mouse PlGF
mAP-0010	Angio Proteomie	100ug	EUR 250

Mouse PLGF-2 PicoKine ELISA Kit
EK0863	BosterBio	96 wells	EUR 510
Description: For Quantitative Detection of mouse PLGF-2 in cell culture supernates, serum and plasma (heparin, EDTA).

Mouse PLGF-2 PicoKine ELISA Kit
MBS1751078-5x96StripWells	MyBiosource	5x96-Strip-Wells	EUR 2755

Mouse PLGF-2 PicoKine ELISA Kit
MBS1751078-96StripWells	MyBiosource	96-Strip-Wells	EUR 600

PLGF (PGF) mouse monoclonal antibody, clone PLGF94, Purified
AM50307PU-S	Origene Technologies GmbH	100 µg	Ask for price

PLGF (PGF) mouse monoclonal antibody, clone PLGF94, Purified
AM50307PU-T	Origene Technologies GmbH	20 µg	Ask for price

Recombinant Mouse PLGF/PGF Protein
MBS9144052-002mg	MyBiosource	0.02mg	EUR 235

Recombinant Mouse PLGF/PGF Protein
MBS9144052-005mg	MyBiosource	0.05mg	EUR 320

Recombinant Mouse PLGF/PGF Protein
MBS9144052-01mg	MyBiosource	0.1mg	EUR 460

Recombinant Mouse PLGF/PGF Protein
MBS9144052-5x01mg	MyBiosource	5x0.1mg	EUR 1900

Purified recombinant Mouse PLGF protein
MBS5308876-001mg	MyBiosource	0.01mg	EUR 380

Purified recombinant Mouse PLGF protein
MBS5308876-5x001mg	MyBiosource	5x0.01mg	EUR 1660

Mouse PLGF / PGF Protein, His Tag
PGF-M52H0	ACROBIOSYSTEMS	50ug	EUR 3327.7
Description: Mouse PLGF, His Tag (PGF-M52H0) is expressed from human 293 cells (HEK293). It contains AA Val 19 - Pro 158 (Accession # P49764-1).

Anti-Rat PlGF Antibody
104-PA04AG	ReliaTech	50 µg	EUR 157.5
Description: Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF1, PlGF2 and PlGF3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF2 has been identified. Mouse PlGF shares 65% amino acid identity with human PlGF2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.

Anti-Rat PlGF Antibody
104-PA04S	ReliaTech	100 µg	EUR 126
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF-1), 152 (PlGF-2), and 203 (PlGF-3) amino acids (aa) respectively. Only PlGF-2 contains a highly basic heparin-binding 21 aa insert at the C-terminus. In rat only one PlGF that is the equivalent of human PlGF-2 has been identified. Rat PlGF shares 60%, 92%, 62% and 59% aa identity with the appropriate isoform of human, mouse, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during human pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt-1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2-mediated angiogenesis. However, PlGF (especially human PlGF-1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF-2, like VEGF164/165, shows heparin-dependent binding of neuropilin (Npn)-1 and Npn-2 and can inhibit nerve growth cone collapse. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis. Circulating PlGF often correlates with tumor stage and aggressiveness, and therapeutic PlGF antibodies are being investigated to inhibit tumor growth and angiogenesis.

Rabbit anti PlGF (human)
102-PA04AG	Angio Proteomie	50ug	EUR 240

Rabbit anti PlGF (human)
102-PA04S	Angio Proteomie	100ug	EUR 240

Rabbit Anti-Rat PlGF
104-PA04	Angio Proteomie	100ug	EUR 240

RABBIT ANTI HUMAN PLGF
MBS222860-01mg	MyBiosource	0.1mg	EUR 660

RABBIT ANTI HUMAN PLGF
MBS222860-5x01mg	MyBiosource	5x0.1mg	EUR 2795

Anti-Human PlGF Antibody
101-M03	ReliaTech	100 µg	EUR 378
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF1), 152 (PlGF2), and 203 (PlGF3) amino acids (aa) respectively. Only PlGF2 contains a highly basic heparinbinding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF2 has been identified. Human PlGF1 shares 56%, 55%, 74% and 95% aa identity with the appropriate isoform of mouse, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2mediated angiogenesis. However, PlGF (especially PlGF1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF2, but not PLGF-1, shows heparindependent binding of neuropilin (Npn)-1 and Npn2. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis.

Anti-Human PlGF Antibody
101-M67	ReliaTech	100 µg	EUR 189
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF1), 152 (PlGF2), and 203 (PlGF3) amino acids (aa) respectively. Only PlGF2 contains a highly basic heparinbinding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF2 has been identified. Human PlGF1 shares 56%, 55%, 74% and 95% aa identity with the appropriate isoform of mouse, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2mediated angiogenesis. However, PlGF (especially PlGF1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF2, but not PLGF-1, shows heparindependent binding of neuropilin (Npn)-1 and Npn2. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis.

Anti-Human PlGF Antibody
101-M69	ReliaTech	100 µg	EUR 189
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF1), 152 (PlGF2), and 203 (PlGF3) amino acids (aa) respectively. Only PlGF2 contains a highly basic heparinbinding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF2 has been identified. Human PlGF1 shares 56%, 55%, 74% and 95% aa identity with the appropriate isoform of mouse, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2mediated angiogenesis. However, PlGF (especially PlGF1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF2, but not PLGF-1, shows heparindependent binding of neuropilin (Npn)-1 and Npn2. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis.

Anti-Human PlGF Antibody
101-MBi67	ReliaTech	50 µg	EUR 189
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF1), 152 (PlGF2), and 203 (PlGF3) amino acids (aa) respectively. Only PlGF2 contains a highly basic heparinbinding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF2 has been identified. Human PlGF1 shares 56%, 55%, 74% and 95% aa identity with the appropriate isoform of mouse, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2mediated angiogenesis. However, PlGF (especially PlGF1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF2, but not PLGF-1, shows heparindependent binding of neuropilin (Npn)-1 and Npn2. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis.

Anti-Human PlGF Antibody
102-P248	ReliaTech	100 µg	EUR 245.7
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF1), 152 (PlGF2), and 203 (PlGF3) amino acids (aa) respectively. Only PlGF2 contains a highly basic heparinbinding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF2 has been identified. Human PlGF1 shares 56%, 55%, 74% and 95% aa identity with the appropriate isoform of mouse, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2mediated angiogenesis. However, PlGF (especially PlGF1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF2, but not PLGF-1, shows heparindependent binding of neuropilin (Npn)-1 and Npn2. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis.

Anti-Human PlGF Antibody
MBS4158489-01mg	MyBiosource	0.1mg	EUR 920

Anti-Human PlGF Antibody
MBS4158489-5x01mg	MyBiosource	5x0.1mg	EUR 3880

Anti-Human PlGF-2 Antibody
101-M65	ReliaTech	100 µg	EUR 246.75
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF1), 152 (PlGF2), and 203 (PlGF3) amino acids (aa) respectively. Only PlGF2 contains a highly basic heparinbinding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF2 has been identified. Human PlGF1 shares 56%, 55%, 74% and 95% aa identity with the appropriate isoform of mouse, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2mediated angiogenesis. However, PlGF (especially PlGF1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF2, but not PLGF-1, shows heparindependent binding of neuropilin (Npn)-1 and Npn2. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis.

Anti-Human PlGF-2 Antibody
101-M65A	ReliaTech	100 µg	EUR 246.75
Description: Placenta Growth Factor-2 (PlGF-2), a 22 kDa protein consisting of 152 amino acid residues is produced as a homodimer. PlGF is a polypeptide growth factor and a member of the platelet-derived growth factor family but more related to vascular endothelial growth factor (VEGF). PlGF acts only as a weak mitogen for those cell types possessing receptors for binding (e.g. vascular endothelial cells). At least one high-affinity receptor for PlGF (FLT-1 or VEGF-R1) has been demonstrated in different primary cell types (e.g. human umbilical vein endothelial cells and monocytes). In addition to its action as a weak mitogen it is also a chemoattractant for monocytes and endothelial cells. Three different proteins are generated by differential splicing of the human PlGF gene: PlGF-1 (131aa native chain), PlGF-2 (152aa) and PlGF-3 (203aa). All 3 mitogens are secretable proteins, but PlGF-2 can bind to heparin with high affinity. PlGF is apparently a homodimer, but preparations of PlGF show some heterogeneity on SDS gels depending of the varying degrees of glycosylation. All dimeric forms possess similar biological activities. Heterodimers between VEGF and PlGF are mitogenic for endothelial cells and have strong angiogenic activity in vivo (e.g. in the CAM assay or in the cornea pocket assay). Different cells and tissues (e.g. placenta) express PlGF-1 and PlGF-2 at different rates. A much related protein of PlGF is VEGF with about 53% homology and VEGF-B with similar biological activities.

OKRC01283-96W - PLGF-2 ELISA Kit (Mouse)
OKRC01283-96W	Aviva Systems Biology	96Wells	EUR 525

Mouse PLGF/PGF HEK293 Overexpression Lysate
MBS8116397-03mg	MyBiosource	0.3mg	EUR 280

Mouse PLGF/PGF HEK293 Overexpression Lysate
MBS8116397-5x03mg	MyBiosource	5x0.3mg	EUR 1205

Mouse PLGF/PGF HEK293 Overexpression Lysate
MBS8116398-03mg	MyBiosource	0.3mg	EUR 280

Mouse PLGF/PGF HEK293 Overexpression Lysate
MBS8116398-5x03mg	MyBiosource	5x0.3mg	EUR 1205

Placenta Growth Factor (PLGF) Polyclonal Antibody (Mouse)
4-PAA114Mu01	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Placenta Growth Factor (PLGF)

Mouse Placenta Growth Factor (PLGF) Protein
20-abx068553	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 10 ug 1 mg 200 ug 50 ug

Mouse Placenta Growth Factor (PLGF) Protein
abx068553-20g	Abbexa	20 µg	EUR 562.5

Mouse Placenta Growth Factor (PLGF) Protein
abx068553-5g	Abbexa	5 µg	EUR 287.5

PLGF(PLGF93) Antibody
BNC810093-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF93), CF680R conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNC810093-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF93), CF680R conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNC810094-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF94), CF680R conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNC810094-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF94), CF680R conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNC430093-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF93), CF543 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNC430093-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF93), CF543 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNC430094-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF94), CF543 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNC430094-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF94), CF543 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNC050093-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF93), CF405M conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNC050093-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF93), CF405M conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNC050094-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF94), CF405M conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNC050094-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF94), CF405M conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNC550093-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF93), CF555 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNC550093-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF93), CF555 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNC550094-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF94), CF555 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNC550094-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF94), CF555 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNC610093-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF93), CF660R conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNC610093-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF93), CF660R conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNC610094-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF94), CF660R conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNC610094-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF94), CF660R conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNC800093-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF93), CF680 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNC800093-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF93), CF680 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNC800094-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF94), CF680 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNC800094-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF94), CF680 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNC700093-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF93), CF770 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNC700093-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF93), CF770 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNC700094-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF94), CF770 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNC700094-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF94), CF770 conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNCP0093-250	Biotium	250uL	EUR 459.6
Description: Primary antibody against PLGF(PLGF93), PerCP conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNCP0094-250	Biotium	250uL	EUR 459.6
Description: Primary antibody against PLGF(PLGF94), PerCP conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNCR0093-250	Biotium	250uL	EUR 459.6
Description: Primary antibody against PLGF(PLGF93), RPE conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNCR0094-250	Biotium	250uL	EUR 459.6
Description: Primary antibody against PLGF(PLGF94), RPE conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNCA0093-250	Biotium	250uL	EUR 459.6
Description: Primary antibody against PLGF(PLGF93), APC conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNCA0094-250	Biotium	250uL	EUR 459.6
Description: Primary antibody against PLGF(PLGF94), APC conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNCAP0093-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF93), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNCAP0093-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF93), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNCAP0094-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF94), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNCAP0094-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF94), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNCH0093-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF93), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

PLGF(PLGF93) Antibody
BNCH0093-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF93), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNCH0094-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against PLGF(PLGF94), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

PLGF(PLGF94) Antibody
BNCH0094-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against PLGF(PLGF94), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Mouse PLGF(Placenta Growth Factor) ELISA Kit
ELK1242-48T	ELK Biotech	48T	Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PLGF. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PLGF. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse PLGF, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse PLGF in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse PLGF(Placenta Growth Factor) ELISA Kit
ELK1242-96T	ELK Biotech	96T	Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PLGF. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PLGF. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse PLGF, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse PLGF in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse PLGF (Placenta Growth Factor) ELISA Kit
MBS8800244-10x96StripWells	MyBiosource	10x96-Strip-Wells	EUR 3130

Mouse PLGF (Placenta Growth Factor) ELISA Kit
MBS8800244-48StripWells	MyBiosource	48-Strip-Wells	EUR 315

Mouse PLGF (Placenta Growth Factor) ELISA Kit
MBS8800244-5x96StripWells	MyBiosource	5x96-Strip-Wells	EUR 1710

Mouse PLGF (Placenta Growth Factor) ELISA Kit
MBS8800244-96StripWells	MyBiosource	96-Strip-Wells	EUR 385

Anti-Human PGF/PlGF Antibody
MBS1569264-01mg	MyBiosource	0.1mg	EUR 375

Anti-Human PGF/PlGF Antibody
MBS1569264-5x01mg	MyBiosource	5x0.1mg	EUR 1390

Anti-Human PlGF (native) Antibody
102-PABi04	ReliaTech	50 µg	EUR 157.5
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF1), 152 (PlGF2), and 203 (PlGF3) amino acids (aa) respectively. Only PlGF2 contains a highly basic heparinbinding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF2 has been identified. Human PlGF1 shares 56%, 55%, 74% and 95% aa identity with the appropriate isoform of mouse, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2mediated angiogenesis. However, PlGF (especially PlGF1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF2, but not PLGF-1, shows heparindependent binding of neuropilin (Npn)-1 and Npn2. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis.

Anti-PGF/Plgf Picoband Antibody
MBS1750586-01mg	MyBiosource	0.1mg	EUR 450

Anti-PGF/Plgf Picoband Antibody
MBS1750586-5x01mg	MyBiosource	5x0.1mg	EUR 1870

Anti-Human PlGF (Peptide) Antibody
102-PA01S	ReliaTech	100 µg	EUR 115.5
Description: Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF1), 152 (PlGF2), and 203 (PlGF3) amino acids (aa) respectively. Only PlGF2 contains a highly basic heparinbinding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF2 has been identified. Human PlGF1 shares 56%, 55%, 74% and 95% aa identity with the appropriate isoform of mouse, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes and some endothelial cells. Circulating PlGF increases during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia. PlGF binds and signals through VEGF R1/Flt1, but not VEGF R2/Flk-1/KDR, while VEGF binds both but signals only through the angiogenic receptor, VEGF R2. PlGF and VEGF therefore compete for binding to VEGF R1, allowing high PlGF to discourage VEGF/VEGF R1 binding and promote VEGF/VEGF R2mediated angiogenesis. However, PlGF (especially PlGF1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF2, but not PLGF-1, shows heparindependent binding of neuropilin (Npn)-1 and Npn2. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing, but also contribute to inflammation in active sickle cell disease and atherosclerosis.

Rabbit Anti-Human PlGF (native)
102-PA04	Angio Proteomie	100ug	EUR 240

Polyclonal Anti-PGF (PLGF) Antibody
GWB-BBP088	GenWay Biotech	0.1 mg	Ask for price

Rabbit Anti-Human PlGF (Peptide)
102-PA01	Angio Proteomie	100ug	EUR 240

PLGF/PGF Protein, Mouse, Recombinant (hFc Tag)
MBS8122547-005mg	MyBiosource	0.05mg	EUR 340

PLGF/PGF Protein, Mouse, Recombinant (hFc Tag)
MBS8122547-05mg	MyBiosource	0.5mg	EUR 1825

PLGF/PGF Protein, Mouse, Recombinant (hFc Tag)
MBS8122547-5x05mg	MyBiosource	5x0.5mg	EUR 8060

Placenta Growth Factor (PLGF) Polyclonal Antibody (Mouse), PE
4-PAA114Mu01-PE	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Placenta Growth Factor (PLGF). This antibody is labeled with PE.

Mouse Placenta Growth Factor (PLGF) ELISA Kit
DLR-PLGF-Mu	DL Develop	96T	EUR 241
Description: serum, plasma, tissue homogenates or other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit
DLR-PLGF-Mu-48T	DL Develop	48T	EUR 380.4
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Placenta Growth Factor (PLGF) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit
DLR-PLGF-Mu-96T	DL Develop	96T	EUR 477.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Placenta Growth Factor (PLGF) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit
DL-PLGF-Mu	DL Develop	96T	EUR 230
Description: serum, plasma, tissue homogenates or other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit
EKL54888-5x96T	Biomatik Corporation	5x96T	EUR 1883.38

Mouse Placenta Growth Factor (PLGF) ELISA Kit
EKL54888-96T	Biomatik Corporation	96T	EUR 396.5

Mouse placenta growth factor,PLGF Elisa kit
EK731467	AFG Bioscience LLC	96 Wells	EUR 0.79

Mouse Placenta Growth Factor (PLGF) ELISA Kit
EKN47757-48T	Biomatik Corporation	48T	EUR 269.71

Mouse Placenta Growth Factor (PLGF) ELISA Kit
EKN47757-5x96T	Biomatik Corporation	5x96T	EUR 1830.18

Mouse Placenta Growth Factor (PLGF) ELISA Kit
EKN47757-96T	Biomatik Corporation	96T	EUR 385.3

Mouse Placenta growth factor (PLGF) ELISA Kit
AE27811MO-48Tests	Abebio	48 Tests	EUR 305
Description: Mouse (Mus musculus)

Mouse Placenta growth factor (PLGF) ELISA Kit
AE27811MO-96Tests	Abebio	96 Tests	EUR 570
Description: Mouse (Mus musculus)

Mouse placenta growth factor, PLGF ELISA kit
CSB-E07401m-24T	Cusabio	1 plate of 24 wells	EUR 198
Description: Quantitativecompetitive ELISA kit for measuring Mouse placenta growth factor, PLGF in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse placenta growth factor, PLGF ELISA kit
1-CSB-E07401m	Cusabio	Ask for price Ask for price Ask for price	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Mouse placenta growth factor, PLGF in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse placenta growth factor,PLGF ELISA kit
CN-02373M1	ChemNorm	96T	EUR 565.2

Mouse placenta growth factor,PLGF ELISA kit
CN-02373M2	ChemNorm	48T	EUR 386.4

Mouse Placenta Growth Factor (PLGF) ELISA Kit
SEA114Mu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 4091.29
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Placenta Growth Factor (PLGF) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit
SEA114Mu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 442.1
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Placenta Growth Factor (PLGF) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit
SEA114Mu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 580.15
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Placenta Growth Factor (PLGF) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit
SEA114Mu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 2250.68
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Placenta Growth Factor (PLGF) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit
4-SEA114Mu	Cloud-Clone	Ask for price Ask for price Ask for price	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Placenta Growth Factor (PLGF) in samples from Serum, plasma, tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse placenta growth factor,PLGF ELISA kit
YLA0480MO-48T	Shanghai YL Biotech	48T	Ask for price

Mouse placenta growth factor,PLGF ELISA kit
YLA0480MO-96T	Shanghai YL Biotech	96T	Ask for price

Mouse placenta growth factor,PLGF ELISA KIT
EA0003Mo	Jiaxing Korain Biotech Ltd (BT Labs)	96 wells	EUR 458

Mouse Placenta growth factor, PlGF ELISA Kit
ELA-E0114m	Nova Lifetech	96tests	EUR 736

Mouse placenta growth factor(PLGF)ELISA Kit
GA-E0088MS-48Tests	GenAsia Biotech	48 Tests	Ask for price

Mouse placenta growth factor(PLGF)ELISA Kit
GA-E0088MS-96Tests	GenAsia Biotech	96 Tests	EUR 460

Mouse placenta growth factor(PLGF)ELISA Kit
GA-E0088MS-48T	GenAsia Biotech	48T	EUR 403.2

Mouse placenta growth factor(PLGF)ELISA Kit
GA-E0088MS-96T	GenAsia Biotech	96T	EUR 640.8

Mouse Placenta Growth Factor (PLGF) ELISA Kit
EKU06646-48T	Biomatik Corporation	48T	EUR 395.36

Mouse Placenta Growth Factor (PLGF) ELISA Kit
EKU06646-5x96T	Biomatik Corporation	5x96T	EUR 2682.8

Mouse Placenta Growth Factor (PLGF) ELISA Kit
EKU06646-96T	Biomatik Corporation	96T	EUR 564.8

Mouse Placenta Growth Factor (PLGF)ELISA Kit
NSL1327m	Sunlong	96 Test	EUR 528

Mouse placenta growth factor(PLGF)ELISA Kit
QY-E21188	Qayee Biotechnology	96T	EUR 433.2

Mouse Placenta growth factor (PLGF) ELISA Kit
RK06233	Abclonal	96T	EUR 280

Mouse Placenta Growth Factor (PLGF) ELISA Kit
RDR-PLGF-Mu-48T	Reddot Biotech	48T	EUR 247.49
Description: serum, plasma, tissue homogenates and other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit
RDR-PLGF-Mu-48Tests	Reddot Biotech	48 Tests	EUR 368.4

Mouse Placenta Growth Factor (PLGF) ELISA Kit
RDR-PLGF-Mu-96T	Reddot Biotech	96T	EUR 353.54
Description: serum, plasma, tissue homogenates and other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit
RDR-PLGF-Mu-96Tests	Reddot Biotech	96 Tests	EUR 501.6

Mouse Placenta Growth Factor (PLGF) ELISA Kit
RD-PLGF-Mu-48T	Reddot Biotech	48T	EUR 235.7
Description: serum, plasma, tissue homogenates and other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit
RD-PLGF-Mu-48Tests	Reddot Biotech	48 Tests	EUR 354

Mouse Placenta Growth Factor (PLGF) ELISA Kit
RD-PLGF-Mu-96T	Reddot Biotech	96T	EUR 336.7
Description: serum, plasma, tissue homogenates and other biological fluids.

Mouse Placenta Growth Factor (PLGF) ELISA Kit
RD-PLGF-Mu-96Tests	Reddot Biotech	96 Tests	EUR 480

Mouse Placenta growth factor (PLGF) ELISA Kit
AE27811MO-48T	Abebio	48T	EUR 305
Description: Mouse (Mus musculus)

Mouse Placenta growth factor (PLGF) ELISA Kit
AE27811MO-96T	Abebio	96T	EUR 570
Description: Mouse (Mus musculus)

Mouse placenta growth factor, PLGF ELISA Kit
MBS1609115-10x96StripWells	MyBiosource	10x96-Strip-Wells	EUR 3955

Mouse placenta growth factor, PLGF ELISA Kit
MBS1609115-5x96StripWells	MyBiosource	5x96-Strip-Wells	EUR 2005

Mouse placenta growth factor, PLGF ELISA Kit
MBS1609115-96StripWells	MyBiosource	96-Strip-Wells	EUR 475

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS2021431-10x96StripWells	MyBiosource	10x96-Strip-Wells	EUR 4070

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS2021431-24StripWells	MyBiosource	24-Strip-Wells	EUR 295

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS2021431-48StripWells	MyBiosource	48-Strip-Wells	EUR 420

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS2021431-5x96StripWells	MyBiosource	5x96-Strip-Wells	EUR 2225

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS2021431-96StripWells	MyBiosource	96-Strip-Wells	EUR 550

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS4501914-10x96Tests	MyBiosource	10x96Tests	EUR 3145

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS4501914-48Tests	MyBiosource	48Tests	EUR 300

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS4501914-5x96Tests	MyBiosource	5x96Tests	EUR 1615

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS4501914-96Test	MyBiosource	96Test	EUR 365

Mouse Placenta Growth Factor (PLGF) ELISA kit
MBS261998-10x96StripWells	MyBiosource	10x96-Strip-Wells	EUR 3290

Mouse Placenta Growth Factor (PLGF) ELISA kit
MBS261998-48StripWells	MyBiosource	48-Strip-Wells	EUR 295

Mouse Placenta Growth Factor (PLGF) ELISA kit
MBS261998-5x96StripWells	MyBiosource	5x96-Strip-Wells	EUR 1800

Mouse Placenta Growth Factor (PLGF) ELISA kit
MBS261998-96StripWells	MyBiosource	96-Strip-Wells	EUR 450

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS2701255-10x96StripWells	MyBiosource	10x96-Strip-Wells	EUR 2275

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS2701255-24StripWells	MyBiosource	24-Strip-Wells	EUR 225

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS2701255-48StripWells	MyBiosource	48-Strip-Wells	EUR 280

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS2701255-5x96StripWells	MyBiosource	5x96-Strip-Wells	EUR 1190

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS2701255-96StripWells	MyBiosource	96-Strip-Wells	EUR 335

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS3805756-10x96StripWells	MyBiosource	10x96-Strip-Wells	EUR 6725

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS3805756-48StripWells	MyBiosource	48-Strip-Wells	EUR 550

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS3805756-5x96StripWells	MyBiosource	5x96-Strip-Wells	EUR 3420

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS3805756-96StripWells	MyBiosource	96-Strip-Wells	EUR 765

Mouse Placenta Growth Factor (PLGF) ELISA Kit
MBS454959-10x96StripWells	MyBiosource	10x96-Strip-Wells	EUR 3070

The outcomes recommend that there’s a must develop further monoclonal antibodies that aren’t affected by the present spike protein mutations.

Antibodies where obtained from Orla Proteins Ltd. London.