Category: NATtrol

Recombinant L-HN Fusion Antigen Derived from the L and HN Domains of Botulinum Neurotoxin B Stimulates a Protective Antibody Response Against Active Neurotoxin

Botulinum neurotoxin (BoNT) is a neurotoxin produced by Clostridium botulinum in an anaerobic setting. BoNT is probably the most poisonous protein amongst micro organism, animals, crops, and chemical substances reported thus far. BoNTs are 150 kDa proteins composed of three main useful domains: catalytic (L area, 50 kDa), translocation (HN area, 50 kDa), and receptor-binding

Read More
Antibody affinity maturation and plasma IgA associate with clinical outcome in hospitalized COVID-19 patients

Hospitalized COVID-19 sufferers usually current with a big spectrum of scientific signs. There’s a vital want to raised perceive the immune responses to SARS-CoV-2 that result in both decision or exacerbation of the scientific illness. Right here, we study longitudinal plasma samples from hospitalized COVID-19 sufferers with differential scientific consequence. We carry out immune-repertoire evaluation

Read More