Antibody affinity maturation and plasma IgA associate with clinical outcome in hospitalized COVID-19 patients
Hospitalized COVID-19 sufferers usually current with a big spectrum of scientific signs. There’s a vital want to raised perceive the immune responses to SARS-CoV-2 that result in both decision or exacerbation of the scientific illness. Right here, we study longitudinal plasma samples from hospitalized COVID-19 sufferers with differential scientific consequence. We carry out immune-repertoire evaluation together with cytokine, hACE2-receptor inhibition, neutralization titers, antibody epitope repertoire, antibody kinetics, antibody isotype and antibody affinity maturation towards the SARS-CoV-2 prefusion spike protein.
Deadly circumstances reveal excessive plasma ranges of IL-6, IL-8, TNFα, and MCP-1, and sustained excessive share of IgA-binding antibodies to prefusion spike in contrast with non-ICU survivors. Illness decision in non-ICU and ICU sufferers associates with antibody binding to the receptor binding motif and fusion peptide, and antibody affinity maturation to SARS-CoV-2 prefusion spike protein. Right here, we offer perception into the immune parameters related to scientific illness severity and disease-resolution consequence in hospitalized sufferers that would inform improvement of vaccine/therapeutics towards COVID-19.
Kaposi sarcoma in anti-neutrophil cytoplasmic antibody-associated vasculitis: a case-based evaluation
Anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) are systemic necrotizing vasculitides related to important morbidity and mortality. Given the immunosuppression used to handle these situations, it will be important for clinicians to acknowledge issues, particularly infectious ones, which can come up throughout therapy. Kaposi sarcoma (KS) is a lymphoangioproliferative neoplasm attributable to human herpes virus 8 (HHV-8). Its cutaneous manifestations can mimic vasculitis.
We describe a 77-year-old man with microscopic polyangiitis with pulmonary-renal syndrome handled with prednisone and intravenous cyclophosphamide who developed KS (HHV-Eight constructive) after 2 months of therapy. Cyclophosphamide was discontinued and prednisone step by step lowered with enchancment and scientific stabilization of KS lesions.
This complete evaluation contains all revealed circumstances of KS in sufferers with AAV, with a aim to summarize potential danger components together with the scientific traits of vasculitis, therapy and outcomes of sufferers with this uncommon complication of immunosuppressive remedy. We additionally expanded our literature evaluation to KS in different types of systemic vasculitis. Our case-based evaluation emphasizes the significance of contemplating infectious issues of immunosuppressive remedy, particularly glucocorticoids, and highlights the uncommon affiliation of KS in systemic vasculitis.

Aggressive Immunoassay of SARS-CoV-2 Utilizing Pig Sera-Derived Anti-SARS-CoV-2 Antibodies
Anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) nucleoprotein (NP) antibodies have been remoted from pig sera utilizing human SARS-CoV-2 NP-immobilized magnetic beads. The binding properties of the remoted antibodies towards SARS-CoV-2 NP have been examined by way of movement cytometry utilizing SARS-CoV-2 NP-immobilized magnetic beads. A aggressive immunoassay was developed for detecting SARS-CoV-2 NP in addition to SARS-CoV-2 within the tradition fluid utilizing magnetic beads with immobilized anti-SARS-CoV-2 NP antibodies. Selectivity assessments have been carried out throughout the aggressive immunoassay for SARS-CoV, MERS-CoV, and CoV pressure 229E within the tradition fluid.
Discount in Nesfatin-1 Ranges within the Cerebrospinal Fluid and Elevated Nigrostriatal Degeneration Following Ventricular Administration of Anti-nesfatin-1 Antibody in Mice
Nesfatin-1 is one among a number of brain-gut peptides which have a detailed relationship with the central dopaminergic system. Our earlier research have proven that nesfatin-1 is able to defending nigral dopaminergic neurons towards 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. A current research additionally revealed a diminished blood degree of nesfatin-1 in sufferers with Parkinson’s illness (PD). The present research was designed to analyze whether or not diminished nesfatin-1 in cerebrospinal fluid (CSF) induces nigrostriatal system degeneration.
An intra-cerebroventricular (ICV) injection approach was used to manage anti-nesfatin-1 antibody straight into the lateral ventricle of the mind. Enzyme-linked immunosorbent assay (ELISA) outcomes confirmed that ICV injection of anti-nesfatin-1 antibody into the lateral ventricle of the mind as soon as day by day for two weeks precipitated a major discount in nesfatin-1 ranges within the CSF (93.1%).
Remedy with anti-nesfatin-1 antibody resulted in a considerable loss (23%) of TH-positive (TH+) dopaminergic neurons within the substantia nigra pars compacta (SNpc), as proven by immunofluorescence staining, a depletion in dopamine and its metabolites within the striatum detected by high-performance liquid chromatography (HPLC), and apparent nuclear shrinkage and mitochondrial lesions in dopaminergic neurons within the SNpc detected by transmission electron microscopy (TEM).
Moreover, the outcomes from our Western blot and ELISA experiments demonstrated that anti-nesfatin-1 antibody injection induced an upregulation of caspase-Three activation, elevated the expression of p-ERK, and elevated brain-derived neurotrophic issue (BDNF) ranges within the SNpc. Taken collectively, these observations recommend that diminished nesfatin-1 within the mind could induce nigrostriatal dopaminergic system degeneration; this impact could also be mediated by way of mitochondrial dysfunction-related apoptosis. Our information help a task of nesfatin-1 in sustaining the conventional physiological perform of the nigrostriatal dopaminergic system.
Convergent antibody evolution and clonotype enlargement following influenza virus vaccination
Current advances in high-throughput single cell sequencing have opened up new avenues into the investigation of B cell receptor (BCR) repertoires. On this research, PBMCs have been collected from 17 human contributors vaccinated with the split-inactivated influenza virus vaccine throughout the 2016-2017 influenza season. A mix of Immune Repertoire Seize (IRCTM) expertise and IgG sequencing was carried out on ~7,800 plasmablast (PB) cells and preferential IgG heavy-light chain pairings have been investigated. In some contributors, a single expanded clonotype accounted for ~22% of their PB BCR repertoire.
Roughly 60% (10/17) of contributors skilled convergent evolution, possessing public PBs that have been elicited independently in a number of contributors. Binding profiles of 1 non-public and three public PBs confirmed they have been all subtype-specific, cross-reactive hemagglutinin (HA) head-directed antibodies.
Anti-RANKL Neutralizing Antibody |
100874-2 |
BPS Bioscience |
100 µg |
EUR 460 |
Description: Human, recombinant monoclonal antibody recognizing the RANKL protein, also known as TNFSF11 antibody and CD254 antibody. This antibody recognizes human RANKL. It has not been tested with other species. MW= 50 kDa (Heavy chain); 24 kDa (Light chain). |
Anti-PCSK9 Neutralizing Antibody |
71207 |
BPS Bioscience |
50 µg |
EUR 555 |
Description: Neutralizing recombinant human antibody (IgG1) recognizing the LDLR binding region of human PCSK9. |
Anti-TIGIT Neutralizing Antibody |
71340 |
BPS Bioscience |
100 µg |
EUR 565 |
Description: Human Anti-TIGIT neutralizing antibody recognizing the TIGIT binding region on immune cells. |
Anti-BCMA Neutralizing Antibody, Mouse IgG1 (recommended for neutralizing assay) |
BCA-M43 |
ACROBIOSYSTEMS |
100ug |
EUR 2354 |
|
Description: Anti-BCMA Neutralizing Antibody, is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with BCMA. |
Anti-PD-1 Neutralizing Antibody |
71120 |
BPS Bioscience |
100 µg |
EUR 465 |
Description: Neutralizing recombinant murine/human chimeric antibody recognizing the PD-L1/PD-L2 binding region of human PD-1. This antibody does not cross-react with mouse PD-1, but does cross-react with monkey (M. fascicularis) PD-1. It has not been tested with other species. |
Anti-IL-17A Neutralizing Antibody |
91015 |
BPS Bioscience |
100 µg |
EUR 490 |
Description: Neutralizing recombinant human_x000D_chimeric antibody recognizing human IL-17A._x000D_This antibody has not been tested for crossreactivity_x000D_with other species. |
Anti-β-Amyloid Neutralizing Antibody |
71223 |
BPS Bioscience |
100 µg |
EUR 465 |
Description: Purified, recombinant, humanized Anti-β-amyloid (IgG1) antibody, expressed in HEK293 cells. This antibody reacts with human β-amyloid and has not been tested for cross-reactivity with other species. |
Anti-CTLA4 (CD152) Neutralizing Antibody |
71212 |
BPS Bioscience |
100 µg |
EUR 490 |
Description: Neutralizing recombinant human monoclonal antibody recognizing the extracellular domain of CTLA4 and blocking binding of CTLA4 to B7.1 and B7.2. This antibody recognizes human CTLA4 but does not bind to murine CTLA4. This antibody has not been tested for cross-reactivity with other species. |
Cytomegalovirus gB Late Neutralizing Antigen (CMV-LA gB Neutralizing) Antibody |
abx411283-02mg |
Abbexa |
0.2 mg |
EUR 678 |
|
Anti-PD-L1 (CD274) Neutralizing Antibody |
71213 |
BPS Bioscience |
100 µg |
EUR 505 |
Description: Neutralizing recombinant chimeric murine/human monoclonal antibody recognizing the extracellular domain of PD-L1 and blocking the binding of PD-L1 to PD-1. This antibody has been shown to cross-react with mouse PD-L1. No other species have been tested. |
Cytomegalovirus gB Late Neutralizing Antigen (CMV-LA gB Neutralizing) Antibody (FITC) |
abx411284-01mg |
Abbexa |
0.1 mg |
EUR 610.8 |
|
Human Cells anti-COVID-19 S-IgM Neutralizing Antibody |
DL99728A-100ul |
DL Develop |
100 ul |
EUR 299 |
|
Description: Spike glycoprotein; S glycoprotein; E2; Peplomer protein |
Human Cells anti-COVID-19 S-IgM Neutralizing Antibody |
DL99728A-50ul |
DL Develop |
50 ul |
EUR 210 |
|
Description: Spike glycoprotein; S glycoprotein; E2; Peplomer protein |
Human Cells anti-COVID-19 S-IgA Neutralizing Antibody |
DL99729A-100ul |
DL Develop |
100 ul |
EUR 299 |
|
Description: Spike glycoprotein; S glycoprotein; E2; Peplomer protein |
Human Cells anti-COVID-19 S-IgA Neutralizing Antibody |
DL99729A-50ul |
DL Develop |
50 ul |
EUR 210 |
|
Description: Spike glycoprotein; S glycoprotein; E2; Peplomer protein |
human anti-CPV neutralizing mAb |
E4A09V04 |
EnoGene |
50ug |
EUR 255 |
Description: Available in various conjugation types. |
human anti-FPV neutralizing mAb |
E4A09V05 |
EnoGene |
50ug |
EUR 255 |
Description: Available in various conjugation types. |
Human Cells anti-COVID-19 S-hIgG1 Neutralizing Antibody |
DL99725A-100ul |
DL Develop |
100 ul |
EUR 299 |
|
Description: Spike glycoprotein; S glycoprotein; E2; Peplomer protein |
Human Cells anti-COVID-19 S-hIgG1 Neutralizing Antibody |
DL99725A-50ul |
DL Develop |
50 ul |
EUR 210 |
|
Description: Spike glycoprotein; S glycoprotein; E2; Peplomer protein |
Anti-COVID-19 S-IgM Neutralizing Antibody |
E38A9973 |
EnoGene |
100ug/100ul |
EUR 225 |
Description: Available in various conjugation types. |
Anti-COVID-19 S-IgA Neutralizing Antibody |
E38A9974 |
EnoGene |
100ug/100ul |
EUR 225 |
Description: Available in various conjugation types. |
Interferon alpha Neutralizing Antibody |
20-abx137013 |
Abbexa |
|
|
|
Anti-COVID-19 S-hIgG1 Neutralizing Antibody |
E38A9970 |
EnoGene |
100ug/100ul |
EUR 225 |
Description: Available in various conjugation types. |
Anti-COVID-19 S-mIgG1 Neutralizing Antibody |
E38A9971 |
EnoGene |
100ug/100ul |
EUR 225 |
Description: Available in various conjugation types. |
Anti-COVID-19 S-cIgG1 Neutralizing Antibody |
E38A9972 |
EnoGene |
100ug/100ul |
EUR 225 |
Description: Available in various conjugation types. |
human anti-FPV/CPV neutralizing mAb |
E409C40-h100 |
EnoGene |
100μL |
EUR 395 |
Description: Available in various conjugation types. |
Anti-2019-nCoV S-IgM Neutralizing Antibody (8A5) |
EPT006 |
ELK Biotech |
50ug |
EUR 239.4 |
|
Description: The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
Anti-2019-nCoV S-IgA Neutralizing Antibody (8A5) |
EPT018 |
ELK Biotech |
50ug |
EUR 239.4 |
|
Description: The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
Anti-NGF (Nerve Growth Factor) Neutralizing Antibody |
100436-1 |
BPS Bioscience |
50 µg |
EUR 355 |
Description: Anti-NGF Neutralizing Recombinant Human antibody. This_x000D_ antibody has not been tested for crossreactivity_x000D_ with other species. |
Anti-NGF (Nerve Growth Factor) Neutralizing Antibody |
100436-2 |
BPS Bioscience |
100 µg |
EUR 490 |
Description: Anti-NGF Neutralizing Recombinant Human antibody. This_x000D_ antibody has not been tested for crossreactivity_x000D_ with other species. |
Anti-PD-1 Neutralizing Antibody, Biotin-labeled |
71215 |
BPS Bioscience |
100 µg |
EUR 510 |
Description: Purified, recombinant, human anti-PD-1 (IgG1) antibody with C-terminal Avitag, expressed in HEK293 cells. Purified antibody was enzymatically biotinylated using Avitag™ technology. This antibody does not cross-react with mouse PD-1, but does cross-react with monkey (M. fascicularis) PD-1. It has not been tested with other species. |
Anti-PD-L1 Neutralizing Antibody, Biotin-labeled |
71214 |
BPS Bioscience |
100 µg |
EUR 510 |
Description: Purified, recombinant, chimeric murine/human anti-PD-L1 (IgG1) antibody with C-terminal Avi-tag, expressed in HEK293 cells. Purified antibody was enzymatically biotinylated using Avitag™ technology. This antibody reacts with human PD-L1 and cross-reacts with mouse PD-L1. It has not been tested for cross-reactivity with other species. |
Anti-2019-nCoV S-hIgG1 Neutralizing Antibody (8A5) |
EPT031 |
ELK Biotech |
50ug |
EUR 239.4 |
|
Description: The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
Anti-2019-nCoV S-mIgG1 Neutralizing Antibody (8A5) |
EPT084 |
ELK Biotech |
50ug |
EUR 239.4 |
|
Description: The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
Anti-2019-nCoV S-cIgG1 Neutralizing Antibody (8A5) |
EPT085 |
ELK Biotech |
50ug |
EUR 239.4 |
|
Description: The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 (AS35) |
SAD-S35 |
ACROBIOSYSTEMS |
100ug |
EUR 2974.6 |
|
Description: Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 (AS35) (SAD-S35) is isolated from a SARS-CoV-2 infected patient and is recombinantly produced from human 293 cells (HEK293). This antibody recognizes the SARS-CoV-2 Spike Protein RBD domain and inhibits the interaction between SARS-CoV-2 RBD and ACE2 with an IC50 of 1.47 μg/mL using SARS-CoV-2 Inhibitor Screening Kit.Pseudovirus assay shows that this antibody has potent neutralizing activity against pseudovirus bearing SARS-CoV-2 Spike protein. |
Mouse anti-COVID-19 S-mIgG1 Neutralizing Antibody |
DL99726A-100ul |
DL Develop |
100 ul |
EUR 299 |
|
Description: Spike glycoprotein; S glycoprotein; E2; Peplomer protein |
Mouse anti-COVID-19 S-mIgG1 Neutralizing Antibody |
DL99726A-50ul |
DL Develop |
50 ul |
EUR 210 |
|
Description: Spike glycoprotein; S glycoprotein; E2; Peplomer protein |
Anti-PCSK9 Neutralizing Antibody, (IgG1) Biotin-labeled |
71216 |
BPS Bioscience |
50 µg |
EUR 530 |
Description: Purified recombinant human_x000D_anti-PCSK9 (IgG1) antibody with a C-terminal_x000D_Avi-tag, expressed in HEK293 cells. Purified_x000D_antibody was enzymatically biotinylated using_x000D_AviTag™ technology. This antibody reacts with_x000D_human PCSK9 and has not been tested for_x000D_cross-reactivity with other species. |
Anti-PCSK9 Neutralizing Antibody, (IgG4) Biotin-labeled |
71217 |
BPS Bioscience |
50 µg |
EUR 515 |
Description: Purified recombinant human_x000D_anti-PCSK9 (IgG4) antibody with a C-terminal_x000D_Avi-tag, expressed in HEK293 cells. Purified_x000D_antibody was enzymatically biotinylated using_x000D_AviTag™ technology. This protein reacts with_x000D_human PCSK9 and has not been tested for_x000D_cross-reactivity with other species. |
Anti-SARS-CoV-2 RBD Potent Neutralizing Antibody, Human IgG1 (AM180) |
SPD-M180 |
ACROBIOSYSTEMS |
100ug |
EUR 2974.6 |
|
Description: Anti-SARS-CoV-2 RBD Potent Neutralizing Antibody, Human IgG1 (AM180) is isolated from a SARS-CoV-2 infected patient and is recombinantly produced from human 293 cells (HEK293). This antibody recognizes the SARS-CoV-2 Spike Protein RBD domain and inhibits the interaction between SARS-CoV-2 RBD and ACE2 with an IC50 of 0.98 μg/mL using SARS-CoV-2 Inhibitor Screening Kit (Cat. No. EP-105).Pseudovirus assay shows that this antibody has potent neutralizing activity against pseudovirus bearing SARS-CoV-2 Spike protein. |
Monoclonal NGF/proNGF Neutralizing Antibody Antibody |
AMM06679G |
Leading Biology |
0.05mg |
EUR 633.6 |
Description: A Monoclonal antibody against Human NGF/proNGF Neutralizing. The antibodies are raised in Mouse. This antibody is applicable in E |
Cynomolgus anti-COVID-19 S-cIgG1 Neutralizing Antibody |
DL99727A-100ul |
DL Develop |
100 ul |
EUR 299 |
|
Description: Spike glycoprotein; S glycoprotein; E2; Peplomer protein |
Cynomolgus anti-COVID-19 S-cIgG1 Neutralizing Antibody |
DL99727A-50ul |
DL Develop |
50 ul |
EUR 210 |
|
Description: Spike glycoprotein; S glycoprotein; E2; Peplomer protein |
Rabbit anti-LukAB pAb (neutralizing) |
0313-001 |
IBT Bioservices |
500ug |
EUR 486 |
Description: - Related to: Staphylococcus
- Applications: Neutralization
|
Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) |
S1N-M122 |
ACROBIOSYSTEMS |
100ug |
EUR 2974.6 |
|
Description: Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike S1 protein. As verified in competitive ELISA-based and pseudovirus-based neutralization assay, this chimeric monoclonal can potently neutralize all SARS-CoV-2 Variants of Concern (VOCs), including Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), Delta (B.1.617.2) and Omicron (B.1.1.529). |
Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgM (AM122) |
SPD-M162 |
ACROBIOSYSTEMS |
100ug |
EUR 2974.6 |
|
Description: Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgM (AM122) is isolated from a SARS-CoV-2 infected patient and is recombinantly produced from human 293 cells (HEK293). |
Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgA1 (AM122) |
SPD-M58P1 |
ACROBIOSYSTEMS |
100ug |
EUR 2974.6 |
|
Description: Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgA1 (AM122) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgA1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike S1 protein. |
Anti-SARS-CoV-2 RBD Potent Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM128) |
SPD-M128 |
ACROBIOSYSTEMS |
100ug |
EUR 2974.6 |
|
Description: Anti-SARS-CoV-2 RBD Potent Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM128) (SPD-M128) is a chimeric monoclonal antibody combining the constant domains of the human IgG1 molecule with mouse variable regions. Pseudovirus assay shows that this antibody has potent neutralizing activity against pseudovirus bearing SARS-CoV-2 Spike protein. |
Spike Neutralizing Antibody (Clone G10xA1) (SARS-CoV-2) |
101326 |
BPS Bioscience |
100 µg |
EUR 600 |
Description: This monoclonal antibody recognizes the SARS-CoV-2 Spike RBD (B.1.1.529, Omicron Variant) protein and neutralizes its interaction with ACE2 [Table of Variants]. The human ACE2 receptor is found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. ACE2 is known to mediate COVID-19 infection through direct binding of the SARS-CoV-2 Spike protein. This neutralizing antibody has been functionally tested using the Spike S1 RBD (B.1.1.529, Omicron Variant) (SARS-CoV-2):ACE2 Inhibitor Screening Colorimetric Assay Kit (BPS Bioscience #78339). |
Spike Neutralizing Antibody (Clone G10xA5) (SARS-CoV-2) |
101327 |
BPS Bioscience |
100 µg |
EUR 600 |
Description: This monoclonal antibody recognizes the SARS-CoV-2 Spike RBD (B.1.1.529, Omicron Variant) protein and neutralizes its interaction with ACE2 [Table of Variants]. The human ACE2 receptor is found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. ACE2 is known to mediate COVID-19 infection through direct binding of the SARS-CoV-2 Spike protein. This neutralizing antibody has been functionally tested using the Spike S1 RBD (B.1.1.529, Omicron Variant) (SARS-CoV-2): ACE2 Inhibitor Screening Colorimetric Assay Kit (BPS Bioscience, #78339). |
Spike S1 Neutralizing Antibody (SARS-CoV-2) (Clone: 414-2) |
100792 |
BPS Bioscience |
100 µg |
EUR 460 |
Description: Recombinant human monoclonal (clone 414-2) antibody recognizing the SARS-CoV-2 Spike S1 RBD glycoprotein. This antibody cross-reacts with the Spike protein from the SARS-CoV virus. |
Spike S1 Neutralizing Antibody (SARS-CoV-2) (Clone: 414-1) |
100793 |
BPS Bioscience |
100 µg |
EUR 485 |
Description: Recombinant human monoclonal (clone 414-1) antibody recognizing the SARS-CoV-2 Spike S1 RBD glycoprotein. This antibody cross-reacts with the Spike protein from the SARS-CoV virus. |
Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Mouse IgG1 (AM122) |
SCT-M369 |
ACROBIOSYSTEMS |
100ug |
EUR 2974.6 |
|
Description: Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Mouse IgG1 (AM122) (SCT-M369), originally from mouse immunized with recombinant SARS-CoV-2 Spike RBD protein, is recombinantly expressed from HEK293 cells. |
Neutralizing Solution |
10750014-1 |
Bio-WORLD |
1 L |
EUR 42.29 |
Spike Neutralizing Antibody (Clone LxC1-G10) (SARS-CoV-2) |
101246 |
BPS Bioscience |
100 µg |
EUR 545 |
Description: This human monoclonal antibody recognizes SARS-CoV-2 full-length spike proteins in the native trimeric conformation. This antibody cross-reacts with the wildtype (BPS Bioscience #100728) as well as the Alpha B.1.1.7 (BPS Bioscience #510334), Beta B.1.351 (BPS Bioscience #510333), Beta B.1.351Δ242-244 (BPS Bioscience #101091), Gamma P.1 (BPS Bioscience #100989), Delta B.1.617.2 (BPS Bioscience #101147) and Delta Plus B.1.617.2.1 (BPS Bioscience #101165) variant spike trimers [Table of variants]. The human ACE2 receptor is found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. ACE2 is known to mediate COVID-19 infection through direct binding of the SARS-CoV-2 Spike protein. This neutralizing antibody has been functionally tested using BPS Bioscience Spike Trimer: ACE2 Inhibitor Screening Kits (available for purchase). |
SeroFlash SARS-CoV-2 Neutralizing Antibody Assay Fast Kit |
D-1008 |
EpiGentek |
|
|
Classical Porcine Fever Virus Neutralizing Antibody ELISA Kit |
RK04111 |
Abclonal |
96T |
EUR 625.2 |
Human-anti-SARS-CoV-2-antibody(Neutralizing) |
E28F04204 |
EnoGene |
N/A |
EUR 1777.78 |
Description: N/A |
Anti-SARS-CoV-2 Spike RBD Broadly Neutralizing Antibody, Human IgG1 (AM359b) (MALS verified) |
SPD-M265 |
ACROBIOSYSTEMS |
100ug |
EUR 5703.1 |
|
Description: The antibody is isolated from the serum of COVID-19 vaccine recipient and is recombinantly produced from human 293 cells (HEK293). This antibody can broadly neutralize SARS-CoV-2 Variants of Concerns (VOCs) including Alpha, Beta, Gamma, Delta and Omicron. |
Anti-SARS-CoV-2 Spike RBD Broadly Neutralizing Antibody, Human IgG2 (AM359b) (MALS verified) |
SPD-M400a |
ACROBIOSYSTEMS |
100ug |
EUR 2974.6 |
|
Description: The antibody is isolated from the serum of COVID-19 vaccine recipient and is recombinantly produced from human 293 cells (HEK293). This antibody can broadly neutralize SARS-CoV-2 Variants of Concerns (VOCs) including Alpha, Beta, Gamma, Delta and Omicron. |
Anti-SARS-CoV-2 Spike RBD Broadly Neutralizing Antibody, Human IgG3 (AM359b) (MALS verified) |
SPD-M401a |
ACROBIOSYSTEMS |
100ug |
EUR 2974.6 |
|
Description: The antibody is isolated from the serum of COVID-19 vaccine recipient and is recombinantly produced from human 293 cells (HEK293). This antibody can broadly neutralize SARS-CoV-2 Variants of Concerns (VOCs) including Alpha, Beta, Gamma, Delta and Omicron. |
Anti-SARS-CoV-2 Spike RBD Broadly Neutralizing Antibody, Human IgG4 (AM359b) (MALS verified) |
SPD-M402a |
ACROBIOSYSTEMS |
100ug |
EUR 2974.6 |
|
Description: The antibody is isolated from the serum of COVID-19 vaccine recipient and is recombinantly produced from human 293 cells (HEK293). This antibody can broadly neutralize SARS-CoV-2 Variants of Concerns (VOCs) including Alpha, Beta, Gamma, Delta and Omicron. |
Cytomegalovirus gH Late Neutralizing Antigen (CMV-LA gH) Antibody |
abx411285-02mg |
Abbexa |
0.2 mg |
EUR 678 |
|
Anti-Bevacizumab Antibody (AY12) (recommended for neutralizing assay) |
BEB-Y12 |
ACROBIOSYSTEMS |
100ug |
EUR 2354 |
|
Description: Mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Bevacizumab F(ab')2. |
PE-Labeled Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) |
SPD-PM226 |
ACROBIOSYSTEMS |
25tests |
EUR 2140 |
|
Description: PE-Labeled Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM122) is a PE-labeled chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike S1 protein. As verified in ELISA, this chimeric monoclonal antibody can bind the spike protein of all SARS-CoV-2 Variants of Concern (VOCs), including Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1) and Delta (B.1.617.2). |
SARS-CoV-2 Neutralizing Monoclonal Antibody [DA0002] |
A73683-100 |
EpiGentek |
100 ul |
EUR 506 |
Anti-SARS-CoV-2 Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) |
RAS-N022 |
ACROBIOSYSTEMS |
96tests |
EUR 631.3 |
|
Description: It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
Anti-SARS-CoV-2 Neutralizing Antibody Quantitative Detection Kit (Spike RBD) |
RAS-N044 |
ACROBIOSYSTEMS |
96tests |
EUR 845.3 |
|
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) poses continual threat to human health due to rapid transmission worldwide.Anti-SARS-CoV-2 Neutralizing Antibody Quantitative Detection Kit (Spike RBD)to test the protective neutralizing antibody levels in post-vaccination serum or convalescent serum. |
Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) (Trehalose free) |
S1N-M12A1 |
ACROBIOSYSTEMS |
100ug |
EUR 270207.1 |
|
Description: Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM122) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike S1 protein. As verified in competitive ELISA-based and pseudovirus-based neutralization assay, this chimeric monoclonal can potently neutralize all SARS-CoV-2 Variants of Concern (VOCs), including Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1) and Delta (B.1.617.2) . |
Horse Anti-Rabies Virus IgG (Fab2), neutralizing |
RBV16-Fab2 |
Alpha Diagnostics |
100 ul |
EUR 534 |
NOVATest VAPERON Neutralizing Antibody Rapid Detection Kit (NOVA Test) |
COVNA-503 |
Atlas Link Technology |
20 Tests |
Ask for price |
Anti-SARS-CoV-2 (B.1.351) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) |
RAS-N031 |
ACROBIOSYSTEMS |
96tests |
EUR 706.2 |
|
Description: It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
Anti-SARS-CoV-2 (B.1.617.2) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) |
RAS-N040 |
ACROBIOSYSTEMS |
96tests |
EUR 706.2 |
|
Description: Multiple variants of SARS-CoV-2 are circulating globally and posting new challenges to human health. As concerns over the potential impacts of the variants grow, people ask if one possesses protective neutralizing antibodies (NAbs) against the variants after receiving the currently available vaccines; and if the NAb therapeutic agents are equally effective to treat the mutant infection as the wild type. To facilitate the mutant-related research, drug trials and vaccine assessments, a high-throughput assay to measure neutralizing antibodies against the mutants is in urgent need. |
Anti-SARS-CoV-2 (B.1.1.529) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) |
RAS-N056 |
ACROBIOSYSTEMS |
96tests |
EUR 706.2 |
|
Description: As of Nov 29th, confirmed cases of a new variant of concern (VOC) B.1.1.529 have been reported in South Africa, Botswana and more than 12 other countries. Thanks to the rapid sequencing efforts of South African scientists, the whole world is now alerted about this potentially devastating lineage, which was assigned the name Omicron by WHO.Omicron is a highly divergent variant with a high number of mutations (26-35) in the spike. Identification of some familiar mutations that also appeared on other VOCs gives rises to concerns of its immune escape potential and higher transmissibility. To facilitate the mutant-related research, drug trials and vaccine development, a high-throughput assay to measure neutralizing antibodies against the mutants is in urgent need. |
Anti-SARS-CoV-2 (B.1.1.7) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) |
RAS-N028 |
ACROBIOSYSTEMS |
96tests |
EUR 706.2 |
|
Description: It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
Anti-SARS-CoV-2 (P.1) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) |
RAS-N034 |
ACROBIOSYSTEMS |
96tests |
EUR 706.2 |
|
Description: It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
Anti-SARS-CoV-2 (BA.2) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) |
RAS-N087 |
ACROBIOSYSTEMS |
96tests |
EUR 706.2 |
|
Description: A more contagious subvariant of omicron, known as BA.2, is spreading across the globe and could soon become the dominant version of Covid-19.It's now the top variant in at least 18 countries and rapidly spreading, representing 35% of all new cases that have been genetically sequenced worldwide, up from 10 countries and 21% of cases the week before, according to new data from the World Health Organization. In the U.S, BA.2 currently makes up 3.8% of genetically sequenced Covid cases, according to the Centers for Disease Control and Prevention.To facilitate the mutant-related research, drug trials and vaccine development, a high-throughput assay to measure neutralizing antibodies against the mutants is in urgent need. |
Anti-SARS-CoV-2 (BA.2.12.1) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) |
RAS-N120 |
ACROBIOSYSTEMS |
96tests |
EUR 706.2 |
|
Description: The newly identified 2019 novel coronavirus (SARS-CoV-2) has posed a serious threat to human health, and it spreads quickly. It is helpful to develop the Anti SARS-CoV-2 neutralizing antibody titer serologic assay kit to test the protective neutralizing antibody level in serum. |
Spike S1 Neutralizing Antibody (VHH), Fc-fusion (IgG1), Avi-Tag (SARS-CoV) |
100784 |
BPS Bioscience |
100 µg |
EUR 595 |
Description: SARS-CoV monoclonal Spike S1 VHH neutralizing antibody, a.a. 1-127(full length), with C-terminal Avi-Tag™ fused to the Fc portion of Human IgG1, expressed in a HEK293 cell expression system. MW = 43 kDa. VHHs are single-domain antibodies from camelids. |
Anti-SARS-CoV-2 (B.1.617.2) Neutralizing Antibody Titer Serologic Assay Kit (Spike Trimer) |
RAS-N041 |
ACROBIOSYSTEMS |
96tests |
EUR 706.2 |
|
Description: Multiple variants of SARS-CoV-2 are circulating globally and posting new challenges to human health. As concerns over the potential impacts of the variants grow, people ask if one possesses protective neutralizing antibodies (NAbs) against the variants after receiving the currently available vaccines; and if the NAb therapeutic agents are equally effective to treat the mutant infection as the wild type. To facilitate the mutant-related research, drug trials and vaccine assessments, a high-throughput assay to measure neutralizing antibodies against the mutants is in urgent need. |
Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Cynomolgus IgG1 (AM122) |
SPD-M201 |
ACROBIOSYSTEMS |
100ug |
EUR 2974.6 |
|
Description: Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Cynomolgus IgG1 (AM122) (SPD-M201) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with Cynomolgus IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike S1 Protein. |
Anti-SARS-CoV-2 (BA.4 & BA.5) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) |
RAS-N107 |
ACROBIOSYSTEMS |
96tests |
EUR 706.2 |
|
Description: The newly identified 2019 novel coronavirus (SARS-CoV-2) has posed a serious threat to human health, and it spreads quickly. It is helpful to develop the Anti SARS-CoV-2 neutralizing antibody titer serologic assay kit to test the protective neutralizing antibody level in serum. |
Biotinylated Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) (MALS verified) |
S1N-VM226 |
ACROBIOSYSTEMS |
25ug |
EUR 1647.8 |
|
Description: Biotinylated Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 (AM122) (S1N-VM226) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike S1 Protein. As verified in competitive ELISA-based and pseudovirus-based neutralization assay, this chimeric monoclonal can potently neutralize all SARS-CoV-2 Variants of Concern (VOCs), including Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1) and Delta (B.1.617.2). |
Spike S1 Neutralizing Antibody (WT, B.1.1.7 and B.1.351 Variant) (Clone C-A11) (SARS-CoV-2) |
101024 |
BPS Bioscience |
100 µg |
EUR 585 |
Description: This purified rabbit monoclonal antibody recognizes recombinant wildtype SARS-CoV-2 Spike RBD and trimeric spike proteins. Additionally, this antibody cross-reacts with the B.1.1.7 variant, originally discovered in the U.K, and the B.1.351 variant, originally discovered in South Africa, for both the Spike RBD and trimeric proteins. This neutralizing antibody impedes the interaction between SARS-CoV-2 spike proteins and ACE2 receptor. ACE2 receptor is known to mediate COVID-19 infection through direct binding of the SARS-CoV2 Spike protein. This neutralizing antibody has been functionally tested using BPS Bioscience Spike RBD: ACE2 Inhibitor Screening Kits (BPS Bioscience, #78018, #78133, #78152). This antibody not been tested for cross reactivity with other SARS-CoV-2 variants. |
Human Monoclonal Anti-Chikungunya virus (CHIKV) E1_E2 protein IgG1 (neutralizing) |
CHIKE13-M |
Alpha Diagnostics |
100 ul |
EUR 578.4 |
Goat Anti-Human Respiratory Syncytial Virus (RSV) IgG, neutralizing |
RSV12-S |
Alpha Diagnostics |
100 ul |
EUR 548.4 |
Spike Trimer Neutralizing Antibody (B.1.617.2, B.1.617.2.1, WT and B.1.1.7 Variants) (Clone hC-A11) (SARS-CoV-2) |
101061 |
BPS Bioscience |
100 µg |
EUR 475 |
Description: This antibody is a humanized monoclonal antibody which recognizes SARS-CoV-2 spike RBD and the full-length spike proteins in the native trimeric conformation. This antibody is derived from rabbit monoclonal C-A11 neutralizing antibody (BPS Bioscience, #101024). It cross-reacts with the wildtype as well as the B.1.617.2 (Delta Variant), B.1.617.2.1 (Delta PLUS Variant), B.1.1.7 (Alpha Variant) RBDs and spike protein trimers [See Table of variants]. The human ACE2 receptor is found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. ACE2 is known to mediate COVID-19 infection through direct binding of the SARS-CoV-2 Sike protein. This neutralizing antibody has been functionally tested using BPS Bioscience Spike RBD: ACE2 Inhibitor Screening Kits (available for purchase). |
Spike S1 Neutralizing Antibody (VHH), Fc-fusion (IgG1), Avi-Tag (SARS-CoV-1), Biotin-labeled |
100785-1 |
BPS Bioscience |
50 µg |
EUR 355 |
Description: SARS-CoV-1 monoclonal Spike S1 VHH neutralizing antibody, a.a. 1-127(full length), with C-terminal Avi-Tag fused to the Fc portion of Human IgG1, expressed in a HEK293 cell expression system. MW = 43 kDa. This protein runs at a higher M.W. by SDS-PAGE due to glycosylation. This protein is enzymatically biotinylated using Avi-Tag™ technology. Biotinylation is confirmed to be ≥90%. VHHs are single-domain antibodies from camelids. |
Spike S1 Neutralizing Antibody (VHH), Fc-fusion (IgG1), Avi-Tag (SARS-CoV-1), Biotin-labeled |
100785-2 |
BPS Bioscience |
100 µg |
EUR 595 |
Description: SARS-CoV-1 monoclonal Spike S1 VHH neutralizing antibody, a.a. 1-127(full length), with C-terminal Avi-Tag fused to the Fc portion of Human IgG1, expressed in a HEK293 cell expression system. MW = 43 kDa. This protein runs at a higher M.W. by SDS-PAGE due to glycosylation. This protein is enzymatically biotinylated using Avi-Tag™ technology. Biotinylation is confirmed to be ≥90%. VHHs are single-domain antibodies from camelids. |
Rabbit Anti-Poliomyelitis Virus 3 (Leon1,Ch,2ab strain) antiserum, neutralizing |
POLV32-S |
Alpha Diagnostics |
100 ul |
EUR 548.4 |
G. Pig anti-Poliomyelitis Virus 3 (sabin strain, native) antiserum, neutralizing |
POLV33-S |
Alpha Diagnostics |
100 ul |
EUR 548.4 |
SARS-CoV-2 Variants Neutralizing Antibody 6-plex Panel (Flow Cytometry Multiplex Bead Assay) |
FCM-N04R |
ACROBIOSYSTEMS |
96tests |
EUR 1187.7 |
|
Description: Since December 2019, the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated disease, COVID-19, has caused a devastating pandemic worldwide.As the virus spreads globally, the continuous emergence of new mutant strains escalated the challenge on humans.To facilitate the mutant-related research, drug trials and vaccine development, a multiplex serological test for assessing antibody responses to mutant strains is in urgent need. |
Rabbit Anti-Poliomyelitis Virus 1 (LSc,2ab strain) antiserum, neutralizing |
POLV16-S |
Alpha Diagnostics |
100 ul |
EUR 548.4 |
Horse Anti-C. tetani purified toxin/Toxoid IgG (Tetanus antitoxin, neutralizing, 300 IU/ml) |
TTOX18-A |
Alpha Diagnostics |
100 ul |
EUR 578.4 |
Horse Anti-C. tetani purified toxin/Toxoid IgG (Tetanus antitoxin, neutralizing, 750 IU/ml) |
TTOX19-A |
Alpha Diagnostics |
100 ul |
EUR 578.4 |
Mouse Monoclonal Anti-HIV-1 gp120 (PND, principal neutralizing domain) IgG |
AB-15110 |
Alpha Diagnostics |
100 ug |
EUR 416.4 |
Mouse monoclonal Anti-MERS Spike protein RBD (MES-RBD) IgG1 (neutralizing) |
MERS125-M |
Alpha Diagnostics |
100 ul |
EUR 578.4 |
Rabbit Anti-Poliomyelitis Virus 2 (P712,Ch,2ab strain) antiserum, neutralizing |
POLV22-S |
Alpha Diagnostics |
100 ul |
EUR 548.4 |
G. Pig anti-Poliomyelitis Virus 2 (sabin strain, native) antiserum, neutralizing |
POLV23-S |
Alpha Diagnostics |
100 ul |
EUR 548.4 |
SARS-CoV-2 Omicron Subvariants Neutralizing Antibody 5-plex Panel (Flow Cytometry Multiplex Bead Assay) |
FCM-N06R |
ACROBIOSYSTEMS |
96tests |
EUR 1187.7 |
|
Description: Since December 2019, the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated disease, COVID-19, has caused a devastating pandemic worldwide. Omicron is a variant of SARS-CoV-2 first detected in November 2021 and is causing the ongoing COVID-19 pandemic. The Omicron subvariants BA.1 and BA.2 of SARS-CoV-2 have dominated the COVID-19 pandemic in early 2022. Its recent descendants BA.2.12.1 and BA.4/5 have surged dramatically to become dominant in the United States and South Africa, respectively. BA.2.12.1 and BA.4/BA.5 exhibit comparable ACE2-binding affinities to BA.2. Importantly, BA.2.12.1 and BA.4/BA.5 display stronger neutralization evasion than BA.2 against the plasma from 3-dose vaccination and, most strikingly, from post-vaccination BA.1 infections. |
Rabbit monoclonal Anti-MERS Spike protein (S1/RBD/MERS-RBD) IgG (Neutralizing) |
MERS122-M |
Alpha Diagnostics |
100 ul |
EUR 781.2 |
Mouse monoclona Anti-Rabies Virus Glycoprotein (RVG) IgG, neutralizing (clone 1) |
RBVGP12-M |
Alpha Diagnostics |
100 ul |
EUR 578.4 |
Mouse monoclona Anti-Rabies Virus Glycoprotein (RVG) IgG, neutralizing (clone 2) |
RBVGP13-M |
Alpha Diagnostics |
100 ul |
EUR 578.4 |
Horse Anti-C. tetani purified toxin/Toxoid IgG (Fab2), Tetanus antitoxin (neutralizing) |
TTOX20-Fab2 |
Alpha Diagnostics |
100 ul |
EUR 534 |
Human Monoclonal Anti-Human Respiratory Syncytial Virus F protein (RSV-F, A2 strain) IgG1 (Neutralizing) |
RSV16-M |
Alpha Diagnostics |
100 ul |
EUR 578.4 |
Mouse-anti-COVID-19/SARS-CoV-2-Monoclonal-Antibody(Neutralizing) |
E40MAV109 |
EnoGene |
N/A |
EUR 346.5 |
Description: N/A |
Collectively, this high-resolution antibody repertoire evaluation demonstrated the influence evolution can have on BCRs in response to influenza virus vaccination, which may information future common influenza prophylactic approaches.
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