Integrin Research The Martin Humphries Lab

Antibody affinity maturation and plasma IgA associate with clinical outcome in hospitalized COVID-19 patients

Hospitalized COVID-19 sufferers usually current with a big spectrum of scientific signs. There’s a vital want to raised perceive the immune responses to SARS-CoV-2 that result in both decision or exacerbation of the scientific illness. Right here, we study longitudinal plasma samples from hospitalized COVID-19 sufferers with differential scientific consequence. We carry out immune-repertoire evaluation together with cytokine, hACE2-receptor inhibition, neutralization titers, antibody epitope repertoire, antibody kinetics, antibody isotype and antibody affinity maturation towards the SARS-CoV-2 prefusion spike protein.

Deadly circumstances reveal excessive plasma ranges of IL-6, IL-8, TNFα, and MCP-1, and sustained excessive share of IgA-binding antibodies to prefusion spike in contrast with non-ICU survivors. Illness decision in non-ICU and ICU sufferers associates with antibody binding to the receptor binding motif and fusion peptide, and antibody affinity maturation to SARS-CoV-2 prefusion spike protein. Right here, we offer perception into the immune parameters related to scientific illness severity and disease-resolution consequence in hospitalized sufferers that would inform improvement of vaccine/therapeutics towards COVID-19.

Kaposi sarcoma in anti-neutrophil cytoplasmic antibody-associated vasculitis: a case-based evaluation

Anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) are systemic necrotizing vasculitides related to important morbidity and mortality. Given the immunosuppression used to handle these situations, it will be important for clinicians to acknowledge issues, particularly infectious ones, which can come up throughout therapy. Kaposi sarcoma (KS) is a lymphoangioproliferative neoplasm attributable to human herpes virus 8 (HHV-8). Its cutaneous manifestations can mimic vasculitis.

We describe a 77-year-old man with microscopic polyangiitis with pulmonary-renal syndrome handled with prednisone and intravenous cyclophosphamide who developed KS (HHV-Eight constructive) after 2 months of therapy. Cyclophosphamide was discontinued and prednisone step by step lowered with enchancment and scientific stabilization of KS lesions.

This complete evaluation contains all revealed circumstances of KS in sufferers with AAV, with a aim to summarize potential danger components together with the scientific traits of vasculitis, therapy and outcomes of sufferers with this uncommon complication of immunosuppressive remedy. We additionally expanded our literature evaluation to KS in different types of systemic vasculitis. Our case-based evaluation emphasizes the significance of contemplating infectious issues of immunosuppressive remedy, particularly glucocorticoids, and highlights the uncommon affiliation of KS in systemic vasculitis.

Aggressive Immunoassay of SARS-CoV-2 Utilizing Pig Sera-Derived Anti-SARS-CoV-2 Antibodies

Anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) nucleoprotein (NP) antibodies have been remoted from pig sera utilizing human SARS-CoV-2 NP-immobilized magnetic beads. The binding properties of the remoted antibodies towards SARS-CoV-2 NP have been examined by way of movement cytometry utilizing SARS-CoV-2 NP-immobilized magnetic beads. A aggressive immunoassay was developed for detecting SARS-CoV-2 NP in addition to SARS-CoV-2 within the tradition fluid utilizing magnetic beads with immobilized anti-SARS-CoV-2 NP antibodies. Selectivity assessments have been carried out throughout the aggressive immunoassay for SARS-CoV, MERS-CoV, and CoV pressure 229E within the tradition fluid.

Discount in Nesfatin-1 Ranges within the Cerebrospinal Fluid and Elevated Nigrostriatal Degeneration Following Ventricular Administration of Anti-nesfatin-1 Antibody in Mice

Nesfatin-1 is one among a number of brain-gut peptides which have a detailed relationship with the central dopaminergic system. Our earlier research have proven that nesfatin-1 is able to defending nigral dopaminergic neurons towards 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. A current research additionally revealed a diminished blood degree of nesfatin-1 in sufferers with Parkinson’s illness (PD). The present research was designed to analyze whether or not diminished nesfatin-1 in cerebrospinal fluid (CSF) induces nigrostriatal system degeneration.

An intra-cerebroventricular (ICV) injection approach was used to manage anti-nesfatin-1 antibody straight into the lateral ventricle of the mind. Enzyme-linked immunosorbent assay (ELISA) outcomes confirmed that ICV injection of anti-nesfatin-1 antibody into the lateral ventricle of the mind as soon as day by day for two weeks precipitated a major discount in nesfatin-1 ranges within the CSF (93.1%).

Remedy with anti-nesfatin-1 antibody resulted in a considerable loss (23%) of TH-positive (TH+) dopaminergic neurons within the substantia nigra pars compacta (SNpc), as proven by immunofluorescence staining, a depletion in dopamine and its metabolites within the striatum detected by high-performance liquid chromatography (HPLC), and apparent nuclear shrinkage and mitochondrial lesions in dopaminergic neurons within the SNpc detected by transmission electron microscopy (TEM).

Moreover, the outcomes from our Western blot and ELISA experiments demonstrated that anti-nesfatin-1 antibody injection induced an upregulation of caspase-Three activation, elevated the expression of p-ERK, and elevated brain-derived neurotrophic issue (BDNF) ranges within the SNpc. Taken collectively, these observations recommend that diminished nesfatin-1 within the mind could induce nigrostriatal dopaminergic system degeneration; this impact could also be mediated by way of mitochondrial dysfunction-related apoptosis. Our information help a task of nesfatin-1 in sustaining the conventional physiological perform of the nigrostriatal dopaminergic system.

Convergent antibody evolution and clonotype enlargement following influenza virus vaccination

Current advances in high-throughput single cell sequencing have opened up new avenues into the investigation of B cell receptor (BCR) repertoires. On this research, PBMCs have been collected from 17 human contributors vaccinated with the split-inactivated influenza virus vaccine throughout the 2016-2017 influenza season. A mix of Immune Repertoire Seize (IRCTM) expertise and IgG sequencing was carried out on ~7,800 plasmablast (PB) cells and preferential IgG heavy-light chain pairings have been investigated. In some contributors, a single expanded clonotype accounted for ~22% of their PB BCR repertoire.

Roughly 60% (10/17) of contributors skilled convergent evolution, possessing public PBs that have been elicited independently in a number of contributors. Binding profiles of 1 non-public and three public PBs confirmed they have been all subtype-specific, cross-reactive hemagglutinin (HA) head-directed antibodies.

Anti-FGFR-5 antibody
STJ93067	St John's Laboratory	200 µl	EUR 197
Description: Rabbit polyclonal to FGFR-5.

Anti-FGFR-4 antibody
STJ97668	St John's Laboratory	200 µl	EUR 197
Description: Rabbit polyclonal to FGFR-4.

Anti-FGFR-4 antibody
STJ98068	St John's Laboratory	100 µl	EUR 234
Description: Mouse monoclonal to FGFR-4.

Anti-FGFR-4 antibody
STJ98069	St John's Laboratory	100 µl	EUR 234
Description: Mouse monoclonal to FGFR-4.

FGFR-3 Polyclonal Antibody
40925-100ul	SAB	100ul	EUR 252

FGFR-3 Polyclonal Antibody
40925-50ul	SAB	50ul	EUR 187

FGFR-3 Polyclonal Antibody
ABP54250-003ml	Abbkine	0.03ml	EUR 158
Immunogen information: Synthesized peptide derived from the Internal region of human FGFR-3 at AA rangle: 100-180 Applications tips:
Description: A polyclonal antibody for detection of FGFR-3 from Human, Mouse, Rat. This FGFR-3 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human FGFR-3 at AA rangle: 100-180

FGFR-3 Polyclonal Antibody
ABP54250-01ml	Abbkine	0.1ml	EUR 289
Immunogen information: Synthesized peptide derived from the Internal region of human FGFR-3 at AA rangle: 100-180 Applications tips:
Description: A polyclonal antibody for detection of FGFR-3 from Human, Mouse, Rat. This FGFR-3 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human FGFR-3 at AA rangle: 100-180

FGFR-3 Polyclonal Antibody
ABP54250-02ml	Abbkine	0.2ml	EUR 414
Immunogen information: Synthesized peptide derived from the Internal region of human FGFR-3 at AA rangle: 100-180 Applications tips:
Description: A polyclonal antibody for detection of FGFR-3 from Human, Mouse, Rat. This FGFR-3 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human FGFR-3 at AA rangle: 100-180

FGFR-3 Polyclonal Antibody
ES5249-100ul	ELK Biotech	100ul	EUR 279
Description: A Rabbit Polyclonal antibody against FGFR-3 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

FGFR-3 Polyclonal Antibody
ES5249-50ul	ELK Biotech	50ul	EUR 207
Description: A Rabbit Polyclonal antibody against FGFR-3 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN	ImmunoStep	50 µg	EUR 349

Anti-Phospho-FGFR-4 (Y642) antibody
STJ90669	St John's Laboratory	200 µl	EUR 197
Description: Rabbit polyclonal to Phospho-FGFR-4 (Y642).

FGFR-5 antibody
22119-100ul	SAB	100ul	EUR 390

FGFR (pY766) Antibody
abx031862-400ul	Abbexa	400 ul	EUR 523
Shipped within 5-10 working days.

FGFR (pY766) Antibody
abx031862-80l	Abbexa	80 µl	EUR 286
Shipped within 5-10 working days.

Rabbit anti-LukAB pAb (neutralizing)
0313-001	IBT Bioservices	500ug	EUR 405
Description: Related to: Staphylococcus Applications: Neutralization

Interferon alpha Neutralizing Antibody
20-abx137013	Abbexa	EUR 356.00 EUR 523.00	0.5 mg 1 mg
Shipped within 5-10 working days.

FGFR (pY653 / 654) Antibody
abx031861-400ul	Abbexa	400 ul	EUR 551
Shipped within 5-10 working days.

FGFR (pY653 / 654) Antibody
abx031861-80l	Abbexa	80 µl	EUR 321
Shipped within 5-10 working days.

FGFR-4 Polyclonal Antibody
ABP57401-003ml	Abbkine	0.03ml	EUR 158
Immunogen information: Synthesized peptide derived from the Internal region of human FGFR-4 Applications tips:
Description: A polyclonal antibody for detection of FGFR-4 from Human. This FGFR-4 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human FGFR-4

FGFR-4 Polyclonal Antibody
ABP57401-01ml	Abbkine	0.1ml	EUR 289
Immunogen information: Synthesized peptide derived from the Internal region of human FGFR-4 Applications tips:
Description: A polyclonal antibody for detection of FGFR-4 from Human. This FGFR-4 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human FGFR-4

FGFR-4 Polyclonal Antibody
ABP57401-02ml	Abbkine	0.2ml	EUR 414
Immunogen information: Synthesized peptide derived from the Internal region of human FGFR-4 Applications tips:
Description: A polyclonal antibody for detection of FGFR-4 from Human. This FGFR-4 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human FGFR-4

FGFR-5 Polyclonal Antibody
ABP55629-003ml	Abbkine	0.03ml	EUR 158
Immunogen information: Synthesized peptide derived from the Internal region of human FGFR-5 at AA range: 130-210 Applications tips:
Description: A polyclonal antibody for detection of FGFR-5 from Human, Mouse. This FGFR-5 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human FGFR-5 at AA range: 130-210

FGFR-5 Polyclonal Antibody
ABP55629-01ml	Abbkine	0.1ml	EUR 289
Immunogen information: Synthesized peptide derived from the Internal region of human FGFR-5 at AA range: 130-210 Applications tips:
Description: A polyclonal antibody for detection of FGFR-5 from Human, Mouse. This FGFR-5 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human FGFR-5 at AA range: 130-210

FGFR-5 Polyclonal Antibody
ABP55629-02ml	Abbkine	0.2ml	EUR 414
Immunogen information: Synthesized peptide derived from the Internal region of human FGFR-5 at AA range: 130-210 Applications tips:
Description: A polyclonal antibody for detection of FGFR-5 from Human, Mouse. This FGFR-5 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human FGFR-5 at AA range: 130-210

FGFR-4 Polyclonal Antibody
ES8394-100ul	ELK Biotech	100ul	EUR 279
Description: A Rabbit Polyclonal antibody against FGFR-4 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

FGFR-4 Polyclonal Antibody
ES8394-50ul	ELK Biotech	50ul	EUR 207
Description: A Rabbit Polyclonal antibody against FGFR-4 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

FGFR-5 Polyclonal Antibody
ES6628-100ul	ELK Biotech	100ul	EUR 279
Description: A Rabbit Polyclonal antibody against FGFR-5 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

FGFR-5 Polyclonal Antibody
ES6628-50ul	ELK Biotech	50ul	EUR 207
Description: A Rabbit Polyclonal antibody against FGFR-5 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Cytomegalovirus gB Late Neutralizing Antigen (CMV-LA gB Neutralizing) Antibody
abx411283-02mg	Abbexa	0.2 mg	EUR 565
Shipped within 1 week.

Anti-VEGF Receptor 3/FLT4 Antibody
A01276-3	BosterBio	100ug/vial	EUR 334

Anti-Human Ki67 Antibody
M00254-3	BosterBio	100ul	EUR 397
Description: Rabbit Polyclonal Human Ki67 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

Anti-Human IBA1 Antibody
M01394-3	BosterBio	100ul	EUR 397
Description: Chicken Polyclonal Human IBA1 Antibody. Validated in IF, IHC, WB and tested in Human.

Anti-14-3-3 alpha + beta Rabbit Monoclonal Antibody
M02431-3	BosterBio	100ug/vial	EUR 397
Description: Rabbit Monoclonal 14-3-3 alpha + beta Antibody. Validated in Flow Cytometry, IP, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Anti-active Caspase-3 Rabbit Monoclonal Antibody
M00334-3	BosterBio	100ug/vial	EUR 397
Description: Anti-active Caspase-3 Rabbit Monoclonal Antibody tested for IF, IHC, ICC, WB in Human

Anti-Galectin 3/LGALS3 Antibody (monoclonal, 12B12)
M00621-3	BosterBio	100ug/vial	EUR 334

Cytomegalovirus gB Late Neutralizing Antigen (CMV-LA gB Neutralizing) Antibody (FITC)
abx411284-01mg	Abbexa	0.1 mg	EUR 509
Shipped within 1 week.

Polyclonal Phospho-FGFR(Y766) Antibody
APR05124G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Phospho-FGFR(Y766) . This antibody is tested and proven to work in the following applications:

Horse Anti-Rabies Virus IgG (Fab2), neutralizing
RBV16-Fab2	Alpha Diagnostics	100 ul	EUR 445

Anti-Glyceraldehyde 3-Phosphate Dehydrogenase [GAPDH] Monoclonal Antibody
M00227-3	BosterBio	100ul	EUR 397
Description: Mouse Monoclonal Glyceraldehyde 3-Phosphate Dehydrogenase [GAPDH] Antibody. Validated in IHC, WB and tested in Equine.

Recombinant Human FGFR-2 Protein
RP00046	Abclonal	5 μg	EUR 136

Recombinant human FGFR-2 Protein
RP01213	Abclonal	10 μg	EUR 155

Monoclonal NGF/proNGF Neutralizing Antibody Antibody
AMM06679G	Leading Biology	0.05mg	EUR 528
Description: A Monoclonal antibody against Human NGF/proNGF Neutralizing. The antibodies are raised in Mouse. This antibody is applicable in E

Goat Anti-Human Respiratory Syncytial Virus (RSV) IgG, neutralizing
RSV12-S	Alpha Diagnostics	100 ul	EUR 457

Anti-RAB3GAP2 Antibody
A07244-3	BosterBio	100ug/vial	EUR 334

Anti-FOXI1 Antibody
A07512-3	BosterBio	100ug/vial	EUR 334

Anti-IL17B Antibody
A10846-3	BosterBio	100ug/vial	EUR 294

Anti-RBMS3 Antibody
A12416-3	BosterBio	100ug/vial	EUR 334

Anti-SENP6 Antibody
A05088-3	BosterBio	100ug/vial	EUR 294

Anti-LBP Antibody
A00809-3	BosterBio	100ug/vial	EUR 294

Anti-IL22 Antibody
A00963-3	BosterBio	100ug/vial	EUR 294

Anti-MBL2 Antibody
A01000-3	BosterBio	100ug/vial	EUR 294

Anti-KCNH1 Antibody
A01036-3	BosterBio	100ug/vial	EUR 294

Anti-IL12B Antibody
A01152-3	BosterBio	100ug/vial	EUR 334

Anti-PRMT1 Antibody
A01417-3	BosterBio	100ug/vial	EUR 294

Anti-TFF3 Antibody
A01738-3	BosterBio	100ug/vial	EUR 334

Anti-IFNAR2 Antibody
A02056-3	BosterBio	100ug/vial	EUR 334

Anti-IL17F Antibody
A02062-3	BosterBio	100ug/vial	EUR 294

Anti-TREM1 Antibody
A02135-3	BosterBio	100ug/vial	EUR 294

Anti-SENP1 Antibody
A02156-3	BosterBio	100ug/vial	EUR 294

Anti-BTC Antibody
A02171-3	BosterBio	100ug/vial	EUR 334

Anti-EEA1 Antibody
A02296-3	BosterBio	100ug/vial	EUR 294

Anti-JAK3 Antibody
A02598-3	BosterBio	100ug/vial	EUR 294

Anti-APRT Antibody
A02721-3	BosterBio	100ug/vial	EUR 334

Anti-CUL2 Antibody
A02986-3	BosterBio	100ug/vial	EUR 334

Anti-EIF4A1 Antibody
A03922-3	BosterBio	100ug/vial	EUR 334

Anti-SLIT1 Antibody
A04113-3	BosterBio	100ug/vial	EUR 294

Anti-SORBS1 Antibody
A04426-3	BosterBio	100ug/vial	EUR 334

Anti-VEGFB Antibody
A04494-3	BosterBio	100ug/vial	EUR 294

Anti-Nanog Antibody
A00153-3	BosterBio	100ug/vial	EUR 294

Anti-IL17C Antibody
A00164-3	BosterBio	100ug/vial	EUR 294

Anti-AICDA Antibody
A00267-3	BosterBio	100ug/vial	EUR 294

Anti-ICOS Antibody
A00291-3	BosterBio	100ug/vial	EUR 334

Anti-TLR1 Antibody
A00429-3	BosterBio	100ug/vial	EUR 334

Anti-IGFBP3 Antibody
A00435-3	BosterBio	100ug/vial	EUR 294

Anti-TANK Antibody
A00445-3	BosterBio	100ug/vial	EUR 334

Anti-FGF23 Antibody
A00478-3	BosterBio	100ug/vial	EUR 294

Anti-Leptin Antibody
A00479-3	BosterBio	100ug/vial	EUR 294

Anti-CD5 Antibody
A00480-3	BosterBio	100ug/vial	EUR 334

Anti-SYK Antibody
A00490-3	BosterBio	100ug/vial	EUR 294

Anti-PON1 Antibody
A00516-3	BosterBio	100ug/vial	EUR 334

Anti-CSF1 Antibody
A00620-3	BosterBio	100ug/vial	EUR 294

Anti-PYROXD1 Antibody
A17214-3	BosterBio	100ug/vial	EUR 334

Anti-CNP Antibody
M01017-3	BosterBio	100ul	EUR 397
Description: Chicken Polyclonal CNP Antibody. Validated in IHC, WB and tested in Equine, Pig.

Anti-GAP43 Antibody
M01868-3	BosterBio	100ul	EUR 397
Description: Rabbit Polyclonal GAP43 Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat.

Anti-Calretinin Antibody
M04255-3	BosterBio	100ul	EUR 397
Description: Rabbit Polyclonal Calretinin Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-MRP1 (human) Monoclonal Antibody (QCRL-1)
M00872-3	BosterBio	1ml	EUR 675
Description: Mouse Monoclonal MRP1 (human) Antibody (QCRL-1). Validated in IP, IF and tested in Human.

D/E NEUTRALIZING AGAR
D04-112-10kg	Alphabiosciences	10 kg	EUR 1536

D/E NEUTRALIZING AGAR
D04-112-2Kg	Alphabiosciences	2 Kg	EUR 373

D/E NEUTRALIZING AGAR
D04-112-500g	Alphabiosciences	500 g	EUR 138

D/E NEUTRALIZING BROTH
D04-115-10kg	Alphabiosciences	10 kg	EUR 1009

D/E NEUTRALIZING BROTH
D04-115-2kg	Alphabiosciences	2kg	EUR 258

D/E NEUTRALIZING BROTH
D04-115-500g	Alphabiosciences	500 g	EUR 107

FGFR-4 (phospho Tyr642) Polyclonal Antibody
ABP54252-003ml	Abbkine	0.03ml	EUR 158
Immunogen information: Synthesized peptide derived from human FGFR-4 around the phosphorylation site of Y642 Applications tips:
Description: A polyclonal antibody for detection of FGFR-4 phospho Tyr642) from Human, Mouse, Rat. This FGFR-4 phospho Tyr642) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human FGFR-4 around the phosphorylation site of Y642

FGFR-4 (phospho Tyr642) Polyclonal Antibody
ABP54252-01ml	Abbkine	0.1ml	EUR 289
Immunogen information: Synthesized peptide derived from human FGFR-4 around the phosphorylation site of Y642 Applications tips:
Description: A polyclonal antibody for detection of FGFR-4 phospho Tyr642) from Human, Mouse, Rat. This FGFR-4 phospho Tyr642) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human FGFR-4 around the phosphorylation site of Y642

FGFR-4 (phospho Tyr642) Polyclonal Antibody
ABP54252-02ml	Abbkine	0.2ml	EUR 414
Immunogen information: Synthesized peptide derived from human FGFR-4 around the phosphorylation site of Y642 Applications tips:
Description: A polyclonal antibody for detection of FGFR-4 phospho Tyr642) from Human, Mouse, Rat. This FGFR-4 phospho Tyr642) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human FGFR-4 around the phosphorylation site of Y642

Collectively, this high-resolution antibody repertoire evaluation demonstrated the influence evolution can have on BCRs in response to influenza virus vaccination, which may information future common influenza prophylactic approaches.